CELA1
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Official Full Name
chymotrypsin-like elastase family, member 1 -
Overview
Elastases form a subfamily of serine proteases that hydrolyze many proteins in addition to elastin. Humans have six elastase genes which encode the structurally similar proteins elastase 1, 2, 2A, 2B, 3A, and 3B. Unlike other elastases, pancreatic elastase 1 is not expressed in the pancreas. To date, elastase 1 expression has only been detected in skin keratinocytes. Clinical literature that describes human elastase 1 activity in the pancreas or fecal material is actually referring to chymotrypsin-like elastase family, member 3B. -
Synonyms
CELA1;chymotrypsin-like elastase family, member 1;ELA1, elastase 1, pancreatic;chymotrypsin-like elastase family member 1;elastase-1;pancreatic elastase 1;elastase 1, pancreatic;ELA1
Recombinant Proteins
- Rat
- Pig
- Human
- Mouse
- Chicken
- Cynomolgus
- Rat pancreas
- Porcine pancreas
- Mammalian Cells
- Wheat Germ
- E.coli
- HEK293
- In Vitro Cell Free System
- Non
- His
- GST
- His&GST
- His&Fc&Avi
Involved Pathway
CELA1 involved in several pathways and played different roles in them. We selected most pathways CELA1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with CELA1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
CELA1 has several biochemical functions, for example, metal ion binding,serine-type endopeptidase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by CELA1 itself. We selected most functions CELA1 had, and list some proteins which have the same functions with CELA1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| serine-type endopeptidase activity | HPR,TYSND1,EGFBP2,GZMK,CTRC,ELA3L,CTRL,FURINB,KLK2,MCPT8 |
| metal ion binding | NTNG1,ZNF804A,DMRT1,CIT,DYTN,SUCLA2,BCKDHA,BCL11B,CSHL1,ZNRF3 |
Interacting Protein
CELA1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CELA1 here. Most of them are supplied by our site. Hope this information will be useful for your research of CELA1.
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