CDK16
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Official Full Name
cyclin-dependent kinase 16 -
Overview
The protein encoded by this gene belongs to the cdc2/cdkx subfamily of the ser/thr family of protein kinases. It may play a role in signal transduction cascades in terminally differentiated cells; in exocytosis; and in transport of secretory cargo from the endoplasmic reticulum. This gene is thought to escape X inactivation. Alternative splicing results in multiple transcript variants encoding different isoforms. -
Synonyms
PCTK1;PCTAIRE;FLJ16665;PCTAIRE1;PCTGAIRE;cyclin-dependent kinase 16;OTTHUMP00000023208;OTTHUMP00000023209;OTTHUMP00000226801;CDK16;cyclin-dependent kinase 16;OTTHUMP00000226803;PCTAIRE-motif protein kinase 1;cell division protein kinase 16;serine/threonine-protein kinase PCTAIRE-1
Recombinant Proteins
- Human
- Mouse
- Sf9 Cells
- E.coli
- Mammalian Cells
- Insect Cells
- HEK293
- GST
- His
- Non
- DDK&Myc
- Avi&Fc&His
Involved Pathway
CDK16 involved in several pathways and played different roles in them. We selected most pathways CDK16 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with CDK16 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
CDK16 has several biochemical functions, for example, ATP binding,cyclin-dependent protein serine/threonine kinase activity,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CDK16 itself. We selected most functions CDK16 had, and list some proteins which have the same functions with CDK16. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein serine/threonine kinase activity | SGK2B,KSR2,SMOK3A,BMPR1BB,PRKACAB,CAMK1GB,ROCK2A,BCKDK,MKNK2,BMPR1AB |
| protein binding | ZNF2,AQP5,HNRNPF,EIF4EBP1,ELAVL1,CD300A,NME5,AGR2,TRAPPC10,DNAJC10 |
| ATP binding | Aatk,DYRK1AA,PBK,NEK4,GLULB,CCT8L2,NSFA,MLH1,RET,RIPK2 |
| cyclin-dependent protein serine/threonine kinase activity | MOK,CDKL1,CDK5,NAT1,CDKL5,CDK10,CCNK,MAK,CDK14,CDK9 |
Interacting Protein
CDK16 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CDK16 here. Most of them are supplied by our site. Hope this information will be useful for your research of CDK16.
SEC23A;ZBTB14;APPBP2;YWHAZ;CCNYL1;YWHAG;SEC24D;BAG6;PKM;CSNK2A2;CDK2;YWHAB
Resources
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References
- Sawant, RR; Jhaveri, AM; et al. The effect of dual ligand-targeted micelles on the delivery and efficacy of poorly soluble drug for cancer therapy. JOURNAL OF DRUG TARGETING 21:630-638(2013).
- Capobianco, G; Marras, V; et al. P16 immunostaining and HPV testing in histological specimens from the uterine cervix. EUROPEAN JOURNAL OF GYNAECOLOGICAL ONCOLOGY 34:227-230(2013).
