CCS

  • Official Full Name

    copper chaperone for superoxide dismutase

  • Overview

    Copper chaperone for superoxide dismutase specifically delivers Cu to copper/zinc superoxide dismutase and may activate copper/zinc superoxide dismutase through direct insertion of the Cu cofactor.

  • Synonyms

    CCS;copper chaperone for superoxide dismutase;superoxide dismutase copper chaperone;MGC138260

Recombinant Proteins

  • Human
  • Rat
  • Mouse
  • Rhesus macaque
  • Zebrafish
  • E.coli
  • Wheat Germ
  • Mammalian Cells
  • In Vitro Cell Free System
  • HEK293
  • GST
  • Non
  • His
  • His&T7
  • His&Fc&Avi
Cat.# Product name Source (Host) Species Tag Protein Length Price
CCS-10894H Recombinant Human CCS, GST-tagged E.coli Human GST 1-274a.a.
CCS-483H Recombinant Human CCS Protein, with Cu (I) E.coli Human Non aa 1-274
CCS-0707H Recombinant Human CCS Protein, GST-Tagged Wheat Germ Human GST
CCS-1230R Recombinant Rat CCS Protein Mammalian Cells Rat His
Ccs-168M Recombinant Mouse Ccs protein E.coli Mouse Non 1-274 a.a.
CCS-189H Recombinant Human CCS protein E.coli Human Non 1-274 a.a.
Ccs-2631M Recombinant Mouse Ccs protein, His & T7-tagged E.coli Mouse His&T7 Ala17~Pro270
Ccs-2632R Recombinant Rat Ccs protein, His & T7-tagged E.coli Rat His&T7 Asp27~Ala268
CCS-31477TH Recombinant Human CCS, His-tagged E.coli Human His 274 amino acids
CCS-31478TH Recombinant Human CCS E.coli Human Non Full L. 1-274 a.a.
CCS-711R Recombinant Rhesus monkey CCS Protein, His-tagged Mammalian Cells Rhesus macaque His
CCS-8011Z Recombinant Zebrafish CCS Mammalian Cells Zebrafish His
CCS-312HCL Recombinant Human CCS cell lysate Human Non
CCS-1053H Recombinant Human CCS protein, His-tagged E.coli Human His Gln23~Gln269
CCS-3038HF Recombinant Full Length Human CCS Protein, GST-tagged In Vitro Cell Free System Human GST Full L. 274 amino acids
CCS-314H Recombinant Human CCS protein, His-tagged E.coli Human His 1-274 aa
CCS-315H Recombinant Human CCS protein, His-T7-tagged E.coli Human His&T7 Gln23~Gln269
CCS-538R Recombinant Rhesus Macaque CCS Protein, His (Fc)-Avi-tagged HEK293 Rhesus macaque His&Fc&Avi
CCS-538R-B Recombinant Rhesus Macaque CCS Protein Pre-coupled Magnetic Beads HEK293 Rhesus macaque
CCS-888R Recombinant Rat CCS Protein, His (Fc)-Avi-tagged HEK293 Rat His&Fc&Avi
CCS-888R-B Recombinant Rat CCS Protein Pre-coupled Magnetic Beads HEK293 Rat

    Involved Pathway

    CCS involved in several pathways and played different roles in them. We selected most pathways CCS participated on our site, such as Amyotrophic lateral sclerosis (ALS), which may be useful for your reference. Also, other proteins which involved in the same pathway with CCS were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Amyotrophic lateral sclerosis (ALS) GRIN2B,MAP2K6,DAXX,MAPK11,PPP3CB,GRIN2D,BAX,BCL2,BCL2L1,APAF1

    Protein Function

    CCS has several biochemical functions, for example, copper ion binding,protein binding,protein disulfide oxidoreductase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by CCS itself. We selected most functions CCS had, and list some proteins which have the same functions with CCS. You can find most of the proteins on our site.

    Function Related Protein
    superoxide dismutase copper chaperone activity ATP7A,PARK7
    superoxide dismutase activity SOD3A,NQO1,SOD2,SOD1,PRNPA
    copper ion binding ATP7A,SCO2,ATOX1,POLR1B,LOXL3B,MOXD1L,ADNP,S100A12,MT1,ABP1
    protein disulfide oxidoreductase activity PTGES2,GLRX5,CHCHD4,DNAJC10,TXN,GSTK1,PTGESL,GLRX2,SH3BGRL3,GLRX3
    protein binding ELL,SMARCA2,GORAB,SUSD2,UBTD1,C1QBP,SNX27,HPCAL4,CBX3,MAPK8
    zinc ion binding BTR02,POLR3K,TRIM52,RNF126,ADH7,ADH5,RFWD2,TRIM60,ALKBH8,PHF8

    Interacting Protein

    CCS has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CCS here. Most of them are supplied by our site. Hope this information will be useful for your research of CCS.

    Resources

    References

    • Zen, Y; Britton, D; et al. Tubulin beta-III: a novel immunohistochemical marker for intrahepatic peripheral cholangiocarcinoma. HISTOPATHOLOGY 65:784-792(2014).
    • Zhu, J; Zhang, J; et al. Cumulus cells accelerate oocyte aging by releasing soluble Fas Ligand in mice. SCIENTIFIC REPORTS 5:-(2015).

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