BST1
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Official Full Name
bone marrow stromal cell antigen 1 -
Overview
Bone marrow stromal cell antigen-1 is a stromal cell line-derived glycosylphosphatidylinositol-anchored molecule that facilitates pre-B-cell growth. The deduced amino acid sequence exhibits 33% similarity with CD38. BST1 expression is enhanced in bone marrow stromal cell lines derived from patients with rheumatoid arthritis. The polyclonal B-cell abnormalities in rheumatoid arthritis may be, at least in part, attributed to BST1 overexpression in the stromal cell population. -
Synonyms
BST1;bone marrow stromal cell antigen 1;ADP-ribosyl cyclase 2;ADP ribosyl cyclase 2;CD157;NAD(+) nucleosidase;BST-1;cADPr hydrolase 2;bone marrow stromal antigen 1;cyclic ADP-ribose hydrolase 2
Recombinant Proteins
- Human
- Mouse
- Rat
- Chicken
- Cynomolgus
- Cryptococcus Neoformans Var. Neoformans Serotype D
- Candida albicans
- E.coli
- HEK293
- Insect Cells
- Mammalian Cells
- Wheat Germ
- Human Cells
- C-His
- In Vitro Cell Free System
- Rabbit
- GST
- His
- T7
- Fc
- Non
- DDK
- Myc
- Avi
Involved Pathway
BST1 involved in several pathways and played different roles in them. We selected most pathways BST1 participated on our site, such as Nicotinate and nicotinamide metabolism,Metabolic pathways,Salivary secretion, which may be useful for your reference. Also, other proteins which involved in the same pathway with BST1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Metabolic pathways | ALDH1A2,ADSS,CYP2C54,IDH1,AMY2A,POLR2C,C1GALT1,PLD1A,NDUFA8,AGK |
| Pancreatic secretion | PRSS2,RYR2,CPA1,SCTR,CLCA5,ATP1A2,AMY2A4,FXYD2,PLA2G2D,CELA2B |
| Nicotinate and nicotinamide metabolism | NADKA,NT5C3L,NT5C2A,NT5E,NT5C1BA,NT5M,NMNAT3,ENPP1,NMNAT2,NADKD1 |
| Salivary secretion | CAP18,CALM1,AMY1B,STATH,VAMP2,PLCB4,CST2,DMBT1,FXYD2,CST3 |
Protein Function
BST1 has several biochemical functions, for example, NAD(P)+ nucleosidase activity,NAD+ nucleosidase activity,phosphorus-oxygen lyase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by BST1 itself. We selected most functions BST1 had, and list some proteins which have the same functions with BST1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| NAD+ nucleosidase activity | ART5,CD38 |
| NAD(P)+ nucleosidase activity | CD38 |
| phosphorus-oxygen lyase activity | GUCY2F,GUCY2E,ADCY1A,ADCY2B,GC3,NPR1A,GC2,CD38,ADCY1B |
| transferase activity | HPRT1L,CAMK2G1,BSK146,JAK2B,ZDHHC23B,MGAT4C,ZDHHC5A,PYGMB,CDK14,HHAT |
Interacting Protein
BST1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with BST1 here. Most of them are supplied by our site. Hope this information will be useful for your research of BST1.
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