BMP10
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Official Full Name
BMP10 bone morphogenetic protein 10 -
Overview
FGF-10 is involved in the initial budding as well as the continuous outgrowth of vertebrate limbs, FGF10 mRNA is expressed preferentially in neurons but not in glial cells and may have a distinct role in the brain. human FGF-10 is mitogenic for fetal rat keratinizing epidermal cells but not for NIH 3T3 cells.Recombinant FGF10 induces the proliferation of human urothelial cells in vitro and induces the proliferation of transitional epithelium. FGF-10 is secreted by cultured mouse pre-adipocytes, prevention of FGF-10 signaling inhibits subsequent differentiation. The ability of embryonic fibroblasts derived from FGF-10 knock-out mice to differentiate into adipocytes is also impaired. -
Synonyms
BMP10;bone morphogenetic protein 10;MGC126783
Recombinant Proteins
- Human
- Mouse
- Chicken
- Zebrafish
- Rat
- CHO
- Mammalian Cells
- Wheat Germ
- E.coli
- HEK293
- In Vitro Cell Free System
- Non
- His
- GST
- Avi&Fc&His
- GST&His
Involved Pathway
BMP10 involved in several pathways and played different roles in them. We selected most pathways BMP10 participated on our site, such as Elastic fibre formation,Extracellular matrix organization,Heart Development, which may be useful for your reference. Also, other proteins which involved in the same pathway with BMP10 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Heart Development | HEY2,FOXC1,HEY1,GATA6,IRX4,SMYD1,NKX2,FOXC2,TBX5,TBX20 |
| Extracellular matrix organization | BGNA,LRP4,FAM49BA,COL1A1,COL10A1,COL17A1,COL4A5,MFAP5,COL15A1B,CTS7 |
| Molecules associated with elastic fibres | MFAP2,FBLN2,EFEMP2,LTBP3,MFAP5,LTBP4,EFEMP1,MFAP4,FBLN1,MFAP1 |
| Elastic fibre formation | FBLN2,LOXL2,LOXL1,FBN2,MFAP5,LOXL3,LOXL4,LTBP4,MFAP1B,MFAP4 |
Protein Function
BMP10 has several biochemical functions, for example, cytokine activity,growth factor activity,hormone activity. Some of the functions are cooperated with other proteins, some of the functions could acted by BMP10 itself. We selected most functions BMP10 had, and list some proteins which have the same functions with BMP10. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | JMJD6,TMEM173,AP1G1,ABCC2,PRIMPOL,RNF183,PSIP1,ISY1,RAB11FIP2,OFCC1 |
| hormone activity | LEPB,INS2,GAST,INHBB,PRL2C2,FNDC5B,HAMP,INSB,CRHR2,IGF1 |
| cytokine activity | IL1B,CD70,CER1,BMP2,BMP8B,GDF5,CCL38A.4,WNT7A,IFNPHI1,TNFSF8 |
| transforming growth factor beta receptor binding | GDF9,TGFBR3,BMP15,TGFBRAP1,GDF5,GDF6B,NDR1,LEFTY2,INHBE,LRG1 |
| growth factor activity | CSF1A,FGF1B,FGF11A,COL20A1,THBS4,PTN,FGF16,MANF,FGF8B,Il2 |
| telethonin binding | MYOZ2,KCNE1,CSRP3,TTN |
Interacting Protein
BMP10 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with BMP10 here. Most of them are supplied by our site. Hope this information will be useful for your research of BMP10.
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