BEX1

  • Official Full Name

    brain expressed, X-linked 1

  • Overview

    Bex1 is a signaling adapter molecule involved in p75NTR/NGFR signaling. It is thought to play a role in cell cycle progression and neuronal differentiation. Bex1 inhibits neuronal differentiation in response to nerve growth factor (NGF). Bex1 has also been implicated as a tumor suppressor.

  • Synonyms

    BEX1;brain expressed, X-linked 1;BEX2;HBEX2;HGR74-h;protein BEX1;brain-expressed X-linked protein 1;ovarian granulosa cell 13.0 kDa protein hGR74

Recombinant Proteins

  • Human
  • Mouse
  • Cynomolgus
  • Rat
  • Wheat Germ
  • E.coli
  • Mammalian Cell
  • HEK293
  • In Vitro Cell Free System
  • HEK293T
  • GST
  • His
  • Non
  • His&Fc&Avi
  • Myc&DDK

    Involved Pathway

    BEX1 involved in several pathways and played different roles in them. We selected most pathways BEX1 participated on our site, such as p75(NTR)-mediated signaling, which may be useful for your reference. Also, other proteins which involved in the same pathway with BEX1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    p75(NTR)-mediated signaling RTN4,NDN,PRDM4,MAGEH1,OMG,ZNF274,RTN4R

    Protein Function

    BEX1 has several biochemical functions, for example, RNA polymerase II activating transcription factor binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by BEX1 itself. We selected most functions BEX1 had, and list some proteins which have the same functions with BEX1. You can find most of the proteins on our site.

    Function Related Protein
    protein binding CD93,FANCC,NT5C2,C9orf9,AMPD2,PRKRIR,PARP1,NF1,ZNF79,KLHL6
    RNA polymerase II activating transcription factor binding HIPK2,EGR2,NHLH2,SMAD3,LMO2,HNF4A,DUSP26,POU1F1,LDB1,TBX20

    Interacting Protein

    BEX1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with BEX1 here. Most of them are supplied by our site. Hope this information will be useful for your research of BEX1.

    TEX11;MDFI;BCAR3;BAG4;CHEK2;CDH1;FGFR2;PIK3CA;GSK3B;PTEN;PAX2;SMAD4;CASP8;FBXW7

    Resources

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