ARL2
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Official Full Name
ADP-ribosylation factor-like 2 -
Overview
This gene encodes a small GTP-binding protein of the RAS superfamily which functions as an ADP-ribosylation factor (ARF). The encoded protein is one of a functionally distinct group of ARF-like genes. -
Synonyms
ARL2;ADP-ribosylation factor-like 2;ADP-ribosylation factor-like protein 2;ARFL2;ADP ribosylation factor like 2;Arl184;ARL2_HUMAN
Recombinant Proteins
- Human
- Zebrafish
- Mouse
- Rat
- E.coli
- Mammalian Cell
- E.Coli or Yeast
- Wheat Germ
- HEK293
- In Vitro Cell Free System
- HEK293T
- GST
- His
- Non
- Myc&DDK
- His&Fc&Avi
Involved Pathway
ARL2 involved in several pathways and played different roles in them. We selected most pathways ARL2 participated on our site, such as Integration of energy metabolism,Metabolism,Metabolism of proteins, which may be useful for your reference. Also, other proteins which involved in the same pathway with ARL2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Metabolism of proteins | LMAN2L,TBCB,EEF1G,TMED10,MPDU1,NSMCE2,CBX4,TIMM17B,TUBA1B,ATPBD4 |
| Metabolism | FAM213B,KIAA1199,MTF1,ACOT9.1,LSM1,PTGDSA,SGMS2,COX6C,DHCR24,SLC52A3 |
| Integration of energy metabolism | KCNJ11,GNG13B,KCNC2,RAPGEF4,AKAP5,MARCKSB,SYT5,RAPGEF3,KCNB1,MARCKSA |
| Post-chaperonin tubulin folding pathway | TBCB,TBCA,TBCE,TBCD,SERPINA7,TBCC |
| Protein folding | VBP1,TBCE,PFDN4,FBXW5,TBCA,SERPINA7,TBCC,CCT6A,PFDN5,PFDN2 |
| Regulation of insulin secretion | KCNS3A,KCNS3,MARCKSA,KCNC2,ARL2BP,SYT5,MARCKSB,KCNB1 |
Protein Function
ARL2 has several biochemical functions, for example, GDP binding,GTP binding,GTPase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ARL2 itself. We selected most functions ARL2 had, and list some proteins which have the same functions with ARL2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| GTPase inhibitor activity | TNK2,CPEB2,SLIT2,IPO5,CDC42SE1,GPS1,RTKN,GPS2,RHOH,UBE4A |
| protein binding | MMP9,GP6,NR2F2,PID1,FHL3,TSSK3,GRIA2,NUDT1,ITGB4,ADAM17 |
| GDP binding | RAB4A,RAB27B,MIEF1,PCK1,RAB35,RAB8A,EIF2B1,SRP54B,RAN,RAP2B |
| GTP binding | AGAP2,ARF3,ARF1L,TUBB2B,RAB39A,DNM3,TUBB4A,RRAS2,SRP54B,RAB18A |
| GTPase activity | GNG3,RAB17,RAB8B,RAB1BB,TUBE1,RAB34A,RAB9B,RNF112,GNL3,RAB11B |
Interacting Protein
ARL2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ARL2 here. Most of them are supplied by our site. Hope this information will be useful for your research of ARL2.
PDE6D;UNC119;ARL2BP
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