ARHGDIA
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Official Full Name
Rho GDP dissociation inhibitor (GDI) alpha -
Overview
Rho family small GTPases, including Rho, Rac and cdc42, act as molecular switches, regulating processes such as cell migration, adhesion, proliferation and differentiation. They are activated by guanine nucleotide exchange factors (GEFs), which catalyze t -
Synonyms
ARHGDIA;Rho GDP dissociation inhibitor (GDI) alpha;GDIA1;rho GDP-dissociation inhibitor 1;RHOGDI;rho GDI 1;rho-GDI alpha;RHOGDI-1;MGC117248
Recombinant Proteins
- Zebrafish
- Mouse
- Human
- Cynomolgus
- Chicken
- Rat
- Mammalian Cell
- E.coli
- Wheat Germ
- HEK293
- In Vitro Cell Free System
- HEK293T
- His
- Non
- GST
- Myc&DDK
- His&Fc&Avi
Involved Pathway
ARHGDIA involved in several pathways and played different roles in them. We selected most pathways ARHGDIA participated on our site, such as Neurotrophin signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with ARHGDIA were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Neurotrophin signaling pathway | TRAF6,PRDM4,SHC2,MAP2K2,MAPK12,BDNF,PDPK1,ATF4,SH2B2,PIK3CB |
Protein Function
ARHGDIA has several biochemical functions, for example, GTPase activator activity,Rho GDP-dissociation inhibitor activity,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ARHGDIA itself. We selected most functions ARHGDIA had, and list some proteins which have the same functions with ARHGDIA. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| GTPase activator activity | TBC1D4,PGAM5,RASA3,ARHGAP42,TBC1D14,MURC,RAP1GAP,SRGAP1,CDC42EP2,BCR |
| protein binding | CCNDBP1,SDC2,SERINC1,RAVER2,PMP22,TLE3,Fgf15,CSNK1E,CDK9,PRDX4 |
| Rho GDP-dissociation inhibitor activity | ARHGDIG,ARHGDIB |
Interacting Protein
ARHGDIA has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ARHGDIA here. Most of them are supplied by our site. Hope this information will be useful for your research of ARHGDIA.
RAC1;RHOA;CDC42;RDX;TINF2
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