ANO10
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Official Full Name
anoctamin 10 -
Overview
The transmembrane protein encoded by this gene is a member of a family of calcium-activated chloride channels. Defects in this gene may be a cause of autosomal recessive spinocerebellar ataxia-10. Several transcript variants encoding different isoforms have been found for this gene. -
Synonyms
ANO10;anoctamin 10;TMEM16K, transmembrane protein 16K;anoctamin-10;FLJ10375;MGC47890;SCAR10;Hypothetical protein LOC55129;TMEM 16K;Transmembrane protein 16K;OTTHUMP00000164038;OTTHUMP00000164039;OTTHUMP00000209958;OTTHUMP00000209959;OTTHUMP00000209960;TMEM16K
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| ANO10-1697M | Recombinant Mouse ANO10 Protein | Mammalian Cell | Mouse | His |
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| ANO10-4216H | Recombinant Human ANO10 Protein, GST-tagged | Wheat Germ | Human | GST |
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| ANO10-4838HF | Recombinant Full Length Human ANO10 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 392 amino acids |
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| ANO10-567M | Recombinant Mouse ANO10 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| ANO10-567M-B | Recombinant Mouse ANO10 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
ANO10 involved in several pathways and played different roles in them. We selected most pathways ANO10 participated on our site, such as Ion channel transport,Stimuli-sensing channels,Transmembrane transport of small molecules, which may be useful for your reference. Also, other proteins which involved in the same pathway with ANO10 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Transmembrane transport of small molecules | SLC12A5B,SLC3A2A,SLC39A7,CLCN4,SLC6A6,SLCO2A1,CLCN4-2,MATE4,SLC1A2A,SLC10A6 |
| Ion channel transport | TRPA1B,TRPM6,GSDMA2,CLCN2,TRPC4APA,ATP10A,ANO9,OSTM1,TRPV3,MCOLN2 |
| Stimuli-sensing channels | TRPM4A,ASIC1A,TRPV3,CLCN7,ASPH,TRPC4AP,TRPM1,TPCN1,TRPM4C,SLC17A3 |
Protein Function
ANO10 has several biochemical functions, for example, calcium activated cation channel activity,NOT intracellular calcium activated chloride channel activity,NOT phospholipid scramblase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ANO10 itself. We selected most functions ANO10 had, and list some proteins which have the same functions with ANO10. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| NOT phospholipid scramblase activity | ANO5,ANO2 |
| calcium activated cation channel activity | TRPM4C,CATSPER1,TMEM63C,CATSPER2,CALHM1,TRPM4A,ANO6,TRPM5,PKD2L1,TRPM4 |
| NOT intracellular calcium activated chloride channel activity | ANO6,Ano3,ANO8,ANO9,ANO7,ANO5 |
Interacting Protein
ANO10 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ANO10 here. Most of them are supplied by our site. Hope this information will be useful for your research of ANO10.
Tmem173
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