AMBP
-
Official Full Name
alpha-1-microglobulin/bikunin precursor -
Overview
This gene encodes a complex glycoprotein secreted in plasma. The precursor is proteolytically processed into distinct functioning proteins: alpha-1-microglobulin, which belongs to the superfamily of lipocalin transport proteins and may play a role in the regulation of inflammatory processes, and bikunin, which is a urinary trypsin inhibitor belonging to the superfamily of Kunitz-type protease inhibitors and plays an important role in many physiological and pathological processes. This gene is located on chromosome 9 in a cluster of lipocalin genes. -
Synonyms
AMBP;alpha-1-microglobulin/bikunin precursor;A1M;HCP;ITI;UTI;EDC1;HI30;ITIL;IATIL;ITILC
Recombinant Proteins
- Human
- Zebrafish
- Rat
- Mouse
- Chicken
- Cattle
- P.pastoris
- Mammalian Cell
- HEK293
- Human Cell
- E.coli
- Yeast
- Wheat Germ
- In Vitro Cell Free System
- HEK293F
- HEK293T
- Human Urine
- Mammalian cells
- Non
- His
- His&GST
- mFc
- GST
- Myc&DDK
- His&Fc&Avi
- Flag
Involved Pathway
AMBP involved in several pathways and played different roles in them. We selected most pathways AMBP participated on our site, such as Binding and Uptake of Ligands by Scavenger Receptors,Scavenging of heme from plasma,Vesicle-mediated transport, which may be useful for your reference. Also, other proteins which involved in the same pathway with AMBP were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Scavenging of heme from plasma | CD163,HPX,LOC479668,NFX1,HP |
| Binding and Uptake of Ligands by Scavenger Receptors | HYOU1,HP,SAA1,IGLC2,LOC479668,APOBB.1,APOA1B,SPARC,STAB2,HPX |
| Vesicle-mediated transport | GJA5,TGOLN2,GJB5,SEC16B,GJA8,PLDN,HPX,TCEAL4,DTNBP1B,COPB2 |
Protein Function
AMBP has several biochemical functions, for example, IgA binding,calcium channel inhibitor activity,calcium oxalate binding. Some of the functions are cooperated with other proteins, some of the functions could acted by AMBP itself. We selected most functions AMBP had, and list some proteins which have the same functions with AMBP. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | JPH2,STK3,TGFBR3,GTF2B,IRF2,HAUS1,JAK1,FAM151B,TFAP2C,DPH3 |
| IgA binding | FCAMR,IGJ,FCAR |
| protein homodimerization activity | CALCOCO2,DPY30,STK4,MBL1,NR6A1A,AGXT,TFAP2E,CORO1A,Flt3l,SYNDIG1 |
| small molecule binding | LCN15,LCN2,MUP20,PTGDSA,MUP3,PAEP,APODA.2,MUP17,RBP4L,PTGDSB |
| heme binding | CYP3A7,PTGS2A,CYP2X8,CYP3A25,CYP2C55,CYP3C1L2,CYP4A12A,CYP2F1,CYP2N13,Adgb |
| serine-type endopeptidase inhibitor activity | COL6A3,WFDC6B,ITIH3A,SPINT1B,HRG,SERPINB12,SERPINB4,SPINK3,SPINK2,SPOCK1 |
| calcium channel inhibitor activity | FKBP1AA,TNNI3,CCDC109B,PACSIN3,SLC30A1B,FKBP1B,FKBP1AB,SLC30A1A,PHPT1,ITPR1 |
Interacting Protein
AMBP has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with AMBP here. Most of them are supplied by our site. Hope this information will be useful for your research of AMBP.
CTSB;FHL3;orf3_hevbu;eno1;COX8A;STAT3;PIK3CA;GRB2;PIK3R3;DAAM1;d-mannose;q99xu0_strp1
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