AKAP9

  • Official Full Name

    A kinase (PRKA) anchor protein (yotiao) 9

  • Overview

    The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. Alternate splicing of this gene results in at least two isoforms that localize to the centrosome and the Golgi apparatus, and interact with numerous signaling proteins from multiple signal transduction pathways. These signaling proteins include type II protein kinase A, serine/threonine kinase protein kinase N, protein phosphatase 1, protein phosphatase 2a, protein kinase C-epsilon and phosphodiesterase 4D3.

  • Synonyms

    AKAP9;A kinase (PRKA) anchor protein (yotiao) 9;A-kinase anchor protein 9;A kinase anchor protein;350kDa;A kinase anchoring protein 450;AKAP9 BRAF fusion protein;AKAP120 like protein;AKAP350;AKAP450;centrosome and golgi localized protein;CG NAP;HYPERION;KIAA0803;kinase N associated protein;MU RMS 40.16A;PPP1R45;PRKA9;protein kinase A anchoring protein 9;protein phosphatase 1;regulatory subunit 45;YOTIAO;protein yotiao;protein hyperion;AKAP 120-like protein;AKAP9-BRAF fusion protein;kinase N-associated protein;A-kinase anchor protein 350 kDa;A-kinase anchor protein 450 kDa;protein phosphatase 1, regulatory subunit 45;centrosome- and Golgi-localized PKN-associated protein;AKAP-9;CG-NAP;MU-RMS-40.16A
Cat.# Product name Source (Host) Species Tag Protein Length Price
AKAP9-26527TH Recombinant Human AKAP9, His-tagged E.coli Human His 3496-3773 a.a.
AKAP9-405H Recombinant Human AKAP9 Protein, GST-tagged Wheat Germ Human GST
AKAP9-7119C Recombinant Chicken AKAP9 Mammalian Cell Chicken His
ACP6-3722H Recombinant Human ACP6 protein, His-tagged E. coli Human N-His 35-324 aa

    Involved Pathway

    AKAP9 involved in several pathways and played different roles in them. We selected most pathways AKAP9 participated on our site, such as ARMS-mediated activation,Activation of NMDA receptor upon glutamate binding and postsynaptic events,Anchoring of the basal body to the plasma membrane, which may be useful for your reference. Also, other proteins which involved in the same pathway with AKAP9 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Anchoring of the basal body to the plasma membrane MARK4,CCDC123,CEP89,TSGA14,TTBK2,FBF1,MAPRE1B,CEP97,BBS13,CEP72
    CREB phosphorylation through the activation of Ras PDPK1A,NEFLB,SLC14A2,DLG4
    Axon guidance PPP3R1,EPHA7,SPTBN1,DPYSL5A,RGMA,LOC608458,MYL9,UNC5A,ARPC4,GFRA4
    ARMS-mediated activation PAQR3A,KIDINS220B,SPTA1,FRS2,SPRED3,PAQR3B,PTPRA,EGFR,PSMD5,FGF18B
    Cell cycle CCND2,SMC1B,CEP164,ORC6,SGOL1,PTTG1,CP110,ENSAA,SMC1AL,CDC16
    Assembly of the primary cilium CCDC123,WDR19,IFT88,RABL5,EXOC1,B9D2,CSNK1D,DYNC1H1,TTC8,FLR
    CREB phosphorylation through the activation of CaMKII SLC14A2,NETO2,DLG4,CREB1B,NEFLB
    Activation of NMDA receptor upon glutamate binding and postsynaptic events ADCY8,CAMKK1B,DLG4,ADCY3,SLC14A2,ADCY1,NEFLB,NETO2,CREB1,CREB1B

    Protein Function

    AKAP9 has several biochemical functions, for example, ion channel binding,potassium channel regulator activity,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by AKAP9 itself. We selected most functions AKAP9 had, and list some proteins which have the same functions with AKAP9. You can find most of the proteins on our site.

    Function Related Protein
    protein binding PPP1R16A,DYNLT1,CDH23,HNRNPF,BNIP1,BRE,FHL5,LOXL4,NEUROD1,NCAPH2
    potassium channel regulator activity PIAS3,KCNIP1,LRRC26,SGK1,SGK2A,KCNIP4,SGK2,ANK2,AMIGO1,KCNE3
    ion channel binding S100A10,CTNNB1,FAM115C,PRNP,PACS1A,YWHAH,DIAPH1,FHL1,PACS1,HERPUD1
    protein complex scaffold DISC1,AKAP6,CAPN3,DLG1,WWC2,WWC1,SEPT2,CHCHD3,MAGI1B,KLHL17
    protein kinase A regulatory subunit binding AKAP1,EZR,AKAP6,ARFGEF2,AKAP7,PJA2,ACBD3,KCNQ1,AKAP8,ARFGEF1
    receptor binding POU2F1,SRMS,EHHADH,DPP4,PVRL2L,FRK,NTF3,GAS6,F2RL1,CCL15

    Interacting Protein

    AKAP9 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with AKAP9 here. Most of them are supplied by our site. Hope this information will be useful for your research of AKAP9.

    GOLGA2;KDM1A;p29991-pro_0000037946;ORF;PSTPIP1;ELF3;SMYD2;ACTR3B;PUF60;TULP3;TDP2;C1orf94;pbuO;q81mm5_bacan;ybgA

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