ADORA2A
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Official Full Name
Adora2a adenosine A2a receptor -
Synonyms
ADORA2A;adenosine A2a receptor;adenosine receptor A2a;A2a, Rs;A2aR;A2AAR;AA2AR;MGC118414
Recombinant Proteins
- Human
- Mouse
- Guinea pig
- Rat
- Horse
- Mus musculus
- Dog
- HEK293
- Mammalian Cell
- E.Coli or Yeast
- Wheat Germ
- E. coli
- E.coli
- Insect Cell
- In Vitro Cell Free System
- E.coli expression system
- Non
- His
- GST
- N-GST
- N-His
- His&Flag
- His&Fc&Avi
- His&TrxA
Involved Pathway
ADORA2A involved in several pathways and played different roles in them. We selected most pathways ADORA2A participated on our site, such as Activation of TRKA receptors,Adenosine P1 receptors,Alcoholism, which may be useful for your reference. Also, other proteins which involved in the same pathway with ADORA2A were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Alcoholism | HIST1H3A,HDAC10,H2AFV,CALM2,HIST1H2AM,SLC18A1,HIST1H4A,HIST1H2AD,ADORA2B,DDC |
| Adenosine P1 receptors | ADORA3,ADORA2B,ADORA1 |
| GPCR ligand binding | OXGR1A.1,CCR3,CCL19A.2,GPR132B,AGT,NMB,PROKR1,ZFPM2B,XK,EMR4 |
| G alpha (s) signalling events | CGA,ADM2,NPS,ADORA2B,VIP,ADCYAP1B,CALCB,PTH,RAMP1,PTHLHA |
| Activation of TRKA receptors | ADCYAP1,NTF7,ADCYAP1R1 |
| Calcium signaling pathway | EDNRB,TNNC2,GNAL,RYR2,PHKG1B,PDGFRA,NOS3,CD38,ATP2A2,PLCB2 |
| Class A/1 (Rhodopsin-like receptors) | CHRM1,INSL3,RLN3,CCRL2,CCL35.1,ADORA3,OXGR1A.3,CXCR7B,XK,NMBA |
| GPCR downstream signaling | SSTR1,OR7D2,ECT2,EDN3,OPN1LW1,GPRC6A,CCR1,RAMP2,APPB,CCL35.1 |
Protein Function
ADORA2A has several biochemical functions, for example, G-protein coupled adenosine receptor activity,alpha-actinin binding,enzyme binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ADORA2A itself. We selected most functions ADORA2A had, and list some proteins which have the same functions with ADORA2A. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| type 5 metabotropic glutamate receptor binding | HOMER1,DNM3 |
| enzyme binding | UGT1A9,NR5A1,KDM4C,PIAS1,RFC5,POR,USF1,PRKDC,UGT1A7,RPA2 |
| protein heterodimerization activity | ZHX2,INHBA,CUL5,HIST1H2BB,ARNT2,HIST1H2AL,SYT16,HIST1H2AA,LTC4S,EGFR |
| identical protein binding | S100A1,CLDN20,AGXT2L2,MID1,GYPA,LUC7L,E2F7,CIDEB,GRIK5,MAP3K11 |
| protein binding | CHUK,SYK,FOXO4,SP2,FOSL2,CTSL1,INHBA,DPEP1,IL13,CIZ1 |
| G-protein coupled adenosine receptor activity | ADORA2AB,ADORA2AA,ADORA1,ADORA2B,ADORA3,P2RY12 |
| alpha-actinin binding | MYOT,DAG1,LRRC10,PKD2L1,XIRP2,MAGI1,ALMS1,PPARG,RARA,KCNN2 |
Interacting Protein
ADORA2A has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ADORA2A here. Most of them are supplied by our site. Hope this information will be useful for your research of ADORA2A.
CYTH2;NECAB2;USP4
Resources
Research Area
Cancer Drug TargetsInflammatory Mediators
Complement Regulatory Proteins
Immune Checkpoints
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References
