ADAMTS7
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Official Full Name
ADAM metallopeptidase with thrombospondin type 1 motif, 7 -
Overview
The protein encoded by this gene is a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) family. Members of this family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The protein encoded by this gene contains two C-terminal TS motifs. [provided by RefSeq, Jul 2008] -
Synonyms
ADAMTS7;ADAM metallopeptidase with thrombospondin type 1 motif, 7;ADAM-TS7;ADAMTS-7;ADAM-TS 7;A disintegrin and metalloproteinase with thrombospondin motifs 7;COMPase;a disintegrin and metalloprotease with thrombospondin motifs-7 preproprotein;a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 7
Recombinant Proteins
- Human
- Mouse
- Rat
- E.coli
- Wheat Germ
- Mammalian Cells
- HEK293
- Yeast
- His
- GST
- SUMO
- Avi
- Fc
Involved Pathway
ADAMTS7 involved in several pathways and played different roles in them. We selected most pathways ADAMTS7 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with ADAMTS7 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
ADAMTS7 has several biochemical functions, for example, hydrolase activity,metal ion binding,metalloendopeptidase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ADAMTS7 itself. We selected most functions ADAMTS7 had, and list some proteins which have the same functions with ADAMTS7. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| zinc ion binding | TRIM43C,GATAD2B,ZCCHC10,PGLYRP3,TRHDE,RNF169,ADAMTS12,BMI1B,SP110,NR5A5 |
| metallopeptidase activity | ECEL1,C6AST1,ADAMTS16,ADAM9,AGBL1,ADAM10B,ADAM28,ERMP1,ADAM8A,ADAM12 |
| hydrolase activity | PTPRJA,DDX3,EAR4,USB1,PLCH2,SPPL3,ACOT5,ADAM25,ZRANB1B,TMPRSS12 |
| peptidase activity | USP2A,ADAM1B,USP25,FAM105B,AGBL1,CAPN8,PAPPAB,CASP8,CAPN11,TMPRSS13B |
| metalloendopeptidase activity | MMP14B,UQCRC1,ADAMTS10,ADAM32,ADAM10A,ADAM21,NPSN,GM12824,SPG7,ADAM23 |
| metal ion binding | TNNI3,FGD4,GLI2A,TRIM108,RNASEL,ZNF614,KEX2,CNOT6,CDKN1A,BMI1B |
Interacting Protein
ADAMTS7 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ADAMTS7 here. Most of them are supplied by our site. Hope this information will be useful for your research of ADAMTS7.
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