ACSS1
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Official Full Name
acyl-CoA synthetase short-chain family member 1 -
Overview
Cytoplasmic acetyl-CoA synthetase (AceCS1) catalyzes the conversion of acetate and CoA to acetyl-CoA (1, 2). Acetyl-CoA synthesized by AceCS1 is used for fatty acid and lipid biosynthesis (1, 2). Studies suggest that this enzyme is regulated by sterol reg -
Synonyms
ACSS1;acyl-CoA synthetase short-chain family member 1;ACAS2L, acetyl Coenzyme A synthetase 2 (AMP forming) like;acetyl-coenzyme A synthetase 2-like, mitochondrial;AceCS2L;dJ568C11.3;MGC33843;acetate--CoA ligase 2;ACAS2L;ACECS1;FLJ45659
Recombinant Proteins
- Human
- Zebrafish
- Mouse
- E.coli
- Wheat Germ
- Mammalian Cell
- Mammalian cells
- Yeast
- HEK293
- In Vitro Cell Free System
- His
- GST
- Non
- Flag
- His&Fc&Avi
Involved Pathway
ACSS1 involved in several pathways and played different roles in them. We selected most pathways ACSS1 participated on our site, such as Glycolysis / Gluconeogenesis,Pyruvate metabolism,Propanoate metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with ACSS1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Propanoate metabolism | ACSS2,ACACA,MLYCD,ACSS2L,ACSS3,ACAT1,ACACB,ACAT2,DLDH,SUCLA2 |
| Pyruvate metabolism | PKMA,PKLR,PDK3B,ACSS2,PDP1,HAGHL,ALDH9A1,PKMB,LDHBA,PDHA1 |
| Metabolic pathways | ATIC,XDH,LPCAT2,GSS,PPCS,COASY,NT5C3A,RPN2,PPAP2B,NDUFS4 |
| Glycolysis / Gluconeogenesis | ALDH2.2,ENO1B,PFKM,PCK2,TPI1,ALDH3B2,PFKMA,G6PCA.2,BPGM,PCK1 |
| Carbon metabolism | PKM,ENO3,DAK,SDHDA,ALDH6A1,PKMA,OGDHL,RPE,GPT,GPI1 |
Protein Function
ACSS1 has several biochemical functions, for example, AMP binding,ATP binding,acetate-CoA ligase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ACSS1 itself. We selected most functions ACSS1 had, and list some proteins which have the same functions with ACSS1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | VPS52,HOXB7,TNIP2,AAAS,TPT1,HDAC6,EHD3,SFPI1,NUSAP1,DRAXIN |
| AMP binding | APRT,ACSS2,CYB5R3,PYGM,PRPS2,PYGL,PRKAG2,PRKAG1,PRPS1,FBP1 |
| acetate-CoA ligase activity | ACSS2,ACSS3 |
| ATP binding | PCCB,NUBPL,PI4KA,FAM20C,UBE2S,TTLL6,MOK,AARS,GUK1,ACTG2 |
Interacting Protein
ACSS1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ACSS1 here. Most of them are supplied by our site. Hope this information will be useful for your research of ACSS1.
VAC14;CLPP
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References
- Hunter, AM; Leuchter, AF; et al. A genome-wide association study of a sustained pattern of antidepressant response. JOURNAL OF PSYCHIATRIC RESEARCH 47:1157-1165(2013).
- Ma, L; Corl, BA; et al. Transcriptional regulation of lipid synthesis in bovine mammary epithelial cells by sterol regulatory element binding protein-1. JOURNAL OF DAIRY SCIENCE 95:3743-3755(2012).
