ACP1
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Official Full Name
acid phosphatase 1, soluble -
Overview
The product of this gene belongs to the phosphotyrosine protein phosphatase family of proteins. It functions as an acid phosphatase and a protein tyrosine phosphatase by hydrolyzing protein tyrosine phosphate to protein tyrosine and orthophosphate. This enzyme also hydrolyzes orthophosphoric monoesters to alcohol and orthophosphate. This gene is genetically polymorphic, and three common alleles segregating at the corresponding locus give rise to six phenotypes. Each allele appears to encode at least two electrophoretically different isozymes, Bf and Bs, which are produced in allele-specific ratios. Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. -
Synonyms
ACP1;acid phosphatase 1, soluble;low molecular weight phosphotyrosine protein phosphatase;LMW-PTP;LMW-PTPase;adipocyte acid phosphatase;red cell acid phosphatase 1;protein tyrosine phosphatase;acid phosphatase of erythrocyte;cytoplasmic phosphoty
Recombinant Proteins
- Human
- Zebrafish
- Chicken
- Rat
- Mouse
- E.coli
- E. coli
- Human
- Wheat Germ
- Mammalian Cell
- HEK293
- HEK293T
- In Vitro Cell Free System
- GST
- His
- N-His
- Non
- Myc&DDK
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| ACP1-1146H | Recombinant Human ACP1 protein(Met1-His158), GST-tagged | E.coli | Human | GST | 1-158 a.a. | |
| ACP1-9306H | Recombinant Human ACP1, GST-tagged | E.coli | Human | GST | 15-102a.a. | |
| ACP1-4867H | Recombinant Human ACP1 Protein, His tagged | E. coli | Human | His | Ala2-His158 | |
| CALCA-3496H | Recombinant Human CALCA protein, His-tagged | E. coli | Human | N-His | 26-116 aa | |
| ACP1-1068H |
Active Recombinant Human ACP1
|
Human | Human | Non |
|
|
| ACP1-177H |
Active Recombinant Human ACP1 Protein, his-Tagged
|
E.coli | Human | His |
|
|
| ACP1-178H | Recombinant Human ACP1 Protein, GST-Tagged | Wheat Germ | Human | GST |
|
|
| ACP1-2236Z | Recombinant Zebrafish ACP1 | Mammalian Cell | Zebrafish | His |
|
|
| ACP1-26291TH | Recombinant Human ACP1, His-tagged | E.coli | Human | His | 4-158 a.a. |
|
| ACP1-3351C | Recombinant Chicken ACP1 | Mammalian Cell | Chicken | His |
|
|
| Acp1-5710R | Recombinant Rat Acp1 protein, His-tagged | E.coli | Rat | His | Met1~His158 |
|
| ACP1-9083HCL | Recombinant Human ACP1 293 Cell Lysate | HEK293 | Human | Non |
|
|
| ACP1-1123H | Recombinant Human ACP1 Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293T | Human | Myc&DDK |
|
|
| ACP1-1567H | Recombinant Human ACP1 protein, His-tagged | E. coli | Human | His | 173aa(including fusion tag) |
|
| ACP1-2477H | Recombinant Human ACP1 protein | E.coli | Human | Non | 1-158aa |
|
| Acp1-44M | Recombinant Mouse Acp1 Protein, His-tagged | E.coli | Mouse | His | Met1-Tyr158 |
|
| Acp1-45M | Recombinant Mouse Acp1 Protein, His-tagged | E.coli | Mouse | His | Met1-Tyr158 |
|
| ACP1-4837H | Recombinant Human ACP1 Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293T | Human | Myc&DDK |
|
|
| Acp1-514M | Recombinant Mouse Acp1 Protein, MYC/DDK-tagged | HEK293T | Mouse | Myc&DDK |
|
|
| ACP1-800HF | Recombinant Full Length Human ACP1 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 158 amino acids |
|
Involved Pathway
ACP1 involved in several pathways and played different roles in them. We selected most pathways ACP1 participated on our site, such as Adherens junction, which may be useful for your reference. Also, other proteins which involved in the same pathway with ACP1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Adherens junction | AASS,TCF7L1A,ACTN2B,MET,IGF1RB,PTPN1,ACTN3,WAS,RHOAB,PTPRJ |
Protein Function
ACP1 has several biochemical functions, for example, acid phosphatase activity,non-membrane spanning protein tyrosine phosphatase activity,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ACP1 itself. We selected most functions ACP1 had, and list some proteins which have the same functions with ACP1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | CDK4,PLIN3,FAAH,ING5,FBXL8,GUCY1B3,KHDC1A,ANKRD1,C1orf94,KCNJ6 |
| acid phosphatase activity | MINPP1A,ACP2,PAPL,ACP5,MINPP1,PPIP5K2,ACPL2,PXYLP1,ACPT,MINPP1B |
| non-membrane spanning protein tyrosine phosphatase activity | PTPN4,PTPN11,PTPN18,DUSP1,PTPN12,PTPN9 |
Interacting Protein
ACP1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ACP1 here. Most of them are supplied by our site. Hope this information will be useful for your research of ACP1.
EIF1B;NR3C1;EPB41;VHL;EIF6;PAK2;IKBKE;TNIK;FNBP1L;MRPL20;SFMBT1;US3;VCAM1;p27958-pro_0000037566
Resources
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References
- Rollin, J; Pouplard, C; et al. Impact of polymorphisms affecting the ACP1 gene on levels of antibodies against platelet factor4-heparin complexes. JOURNAL OF THROMBOSIS AND HAEMOSTASIS 11:1609-1611(2013).
- Rollin, J; Pouplard, C; et al. Impact of polymorphisms affecting ACP1, which codes for a protein tyrosine phosphatase, on levels of antibodies to platelet factor 4/heparin complexes. JOURNAL OF THROMBOSIS AND HAEMOSTASIS 11:132-132(2013).
