ABLIM1
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Official Full Name
actin binding LIM protein 1 -
Overview
This gene encodes a cytoskeletal LIM protein that binds to actin filaments via a domain that is homologous to erythrocyte dematin. LIM domains, found in over 60 proteins, play key roles in the regulation of developmental pathways. LIM domains also function as protein-binding interfaces, mediating specific protein-protein interactions. The protein encoded by this gene could mediate such interactions between actin filaments and cytoplasmic targets. Alternatively spliced transcript variants encoding different isoforms have been identified. -
Synonyms
ABLIM1;actin binding LIM protein 1;ABLIM, LIMAB1;actin-binding LIM protein 1;abLIM;limatin;RP11-317F20.1;ABLIM 1;abLIM-1;ABLIM-L;ABLIM-M;ABLIM-S;ABLM1_HUMAN;Actin binding double zinc finger protein;Actin binding LIM protein family member 1;Actin-binding double zinc finger protein;Actin-binding LIM protein family member 1;DKFZp781D0148;FLJ14564;KIAA0059;LIM actin binding protein 1;LIMAB 1;LIMAB1;MGC1224;MGC125264;OTTHUMP00000020530;OTTHUMP00000020531;OTTHUMP00000020532;OTTHUMP00000020533;OTTHUMP00000020534;OTTHUMP00000020535;OTTHUMP00000020536;OTTHUMP00000020537;RGD1565768;actin-binding double-zinc-finger protein;actin-binding LIM protein family m
Recombinant Proteins
- Human
- Mouse
- Chicken
- Wheat Germ
- Mammalian Cell
- HEK293
- In Vitro Cell Free System
- GST
- His
- Non
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| ABLIM1-107H | Recombinant Human ABLIM1 Protein, GST-Tagged | Wheat Germ | Human | GST |
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| ABLIM1-108H | Recombinant Human ABLIM1 Protein, GST-Tagged | Wheat Germ | Human | GST |
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| ABLIM1-1143M | Recombinant Mouse ABLIM1 Protein | Mammalian Cell | Mouse | His |
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| ABLIM1-3942C | Recombinant Chicken ABLIM1 | Mammalian Cell | Chicken | His |
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| ABLIM1-9125HCL | Recombinant Human ABLIM1 293 Cell Lysate | HEK293 | Human | Non |
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| ABLIM1-03HF | Recombinant Full Length Human ABLIM1 Protein | In Vitro Cell Free System | Human | Full L. 401 amino acids |
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| ABLIM1-223M | Recombinant Mouse ABLIM1 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| ABLIM1-223M-B | Recombinant Mouse ABLIM1 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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| ABLIM1-26043TH | Recombinant Human ABLIM1 | Wheat Germ | Human | Non | 401 amino acids |
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| ABLIM1-790HF | Recombinant Full Length Human ABLIM1 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 401 amino acids |
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Involved Pathway
ABLIM1 involved in several pathways and played different roles in them. We selected most pathways ABLIM1 participated on our site, such as Axon guidance, which may be useful for your reference. Also, other proteins which involved in the same pathway with ABLIM1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Axon guidance | GPC1A,CDK5,DAB2IPB,CDK5R1B,KLB,PLXND1,TRPC7,EFNA2,RHOC,EFNA1 |
Protein Function
ABLIM1 has several biochemical functions, for example, actin binding,protein binding,zinc ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ABLIM1 itself. We selected most functions ABLIM1 had, and list some proteins which have the same functions with ABLIM1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| zinc ion binding | L3MBTL4,LHX1,DTX3,BRF1,FTR72,MIB2,CXXC5,PDLIM2,LNX2B,PPARAB |
| actin binding | VASP,HDAC6,SNTA1,SNTB2,ESPN,WASF3B,EPB41L3A,FSCN1A,DBNLA,MYBPC1 |
| protein binding | XBP1,ARHGAP44,SMURF2,ITSN2,CARF,TOMM20,NRSN1,CHD7,CEP290,MALSU1 |
Interacting Protein
ABLIM1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ABLIM1 here. Most of them are supplied by our site. Hope this information will be useful for your research of ABLIM1.
CARD9;LDOC1;SFN;PA;VIM;KRT15;GOLGA2;SREBF2;TRAF2;CALCOCO2;USHBP1;TTN;HOOK2;BEGAIN;TSC22D4;Kif1c;YWHAB
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References
- Smith, FD; Samelson, BK; et al. Discovery of cellular substrates for protein kinase A using a peptide array screening protocol. BIOCHEMICAL JOURNAL 438:103-110(2011).
- Ma, C; Yao, Y; et al. Differential Proteomic Analysis of Platelets Suggested Possible Signal Cascades Network in Platelets Treated with Salvianolic Acid B. PLOS ONE 6:-(2011).
