ZBTB7B
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Official Full Name
zinc finger and BTB domain containing 7B -
Overview
ZBTB7B is a transcription factor that acts as a key regulator of lineage commitment of immature T-cell precursors. ZBTB7B is necessary and sufficient for commitment of CD4 lineage, while its absence causes CD8 commitment. Development of immature T-cell pr -
Synonyms
ZBTB7B;zinc finger and BTB domain containing 7B;zinc finger and BTB domain-containing protein 7B;zfp-67;zinc finger protein 67;zinc finger protein Th-POK;T helper-inducing POZ/Krueppel factor;Vzinc finger and BTB domain containing 7B;T-helper-inducing POZ/Krueppel-like factor;krueppel-related zinc finger protein cKrox;Thpok;Zfp67;c-Krox;MGC102577
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| ZBTB7B-3786H | Recombinant Human ZBTB7B, GST-tagged | E.coli | Human | GST | N-term-300aa | |
| ZBTB7B-29517TH | Recombinant Human ZBTB7B, His-tagged | E.coli | Human | His | 539 amino acids |
|
| ZBTB7B-211HCL | Recombinant Human ZBTB7B 293 Cell Lysate | HEK293 | Human | Non |
|
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| ZBTB7B-1275H | Recombinant Human ZBTB7B Protein (G2-S539), Tag Free | Insect Cell | Human | Non | G2-S539 |
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| ZBTB7B-1276H | Recombinant Human ZBTB7B Protein (G2-S539), His/StrepII tagged | Insect Cell | Human | His&StrepII | G2-S539 |
|
| ZBTB7B-21H | Recombinant Human ZBTB7B Protein, GST-tagged | Wheat Germ | Human | GST |
|
Involved Pathway
ZBTB7B involved in several pathways and played different roles in them. We selected most pathways ZBTB7B participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with ZBTB7B were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
ZBTB7B has several biochemical functions, for example, DNA binding,metal ion binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ZBTB7B itself. We selected most functions ZBTB7B had, and list some proteins which have the same functions with ZBTB7B. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| metal ion binding | ZFP330,UGP2,ZFP131,FCER2,NEK10,ALKBH5,CYP2P9,GM5136,TRIM43C,NDUFS7 |
| DNA binding | ZNF146,ZNF224,CEBPA,HOMEZ,IRF2A,TERT,RXRGA,ERCC2,ETV5,SIX7 |
| protein binding | SH3YL1,F10,RTP4,USP19,OSTC,TBCB,CETN3,DNAJB11,MOBP,TAX1BP1 |
Interacting Protein
ZBTB7B has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ZBTB7B here. Most of them are supplied by our site. Hope this information will be useful for your research of ZBTB7B.
IMP4;ZBTB5;NCK2;SORBS3;RPL9P7;BCL6;GRB2
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References
- Cheroutre, H; Husain, MM; et al. CD4 CTL: Living up to the challenge. SEMINARS IN IMMUNOLOGY 25:273-281(2013).
- Nagamine, R; Korenaga, H; et al. Characterization and expression analysis of Th-POK from the Japanese pufferfish, Takifugu rubripes. COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY 164:124-132(2013).
