YEATS4
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Official Full Name
YEATS domain containing 4 -
Overview
The protein encoded by this gene is found in the nucleoli. It has high sequence homology to human MLLT1, and yeast and human MLLT3 proteins. Both MLLT1 and MLLT3 proteins belong to a class of transcription factors, indicating that the encoded protein might also represent a transcription factor. This protein is thought to be required for RNA transcription. This gene has been shown to be amplified in tumors. -
Synonyms
YEATS4;YEATS domain containing 4;YEATS domain-containing protein 4;GAS41;NuBI 1;YAF9;4930573H17Rik;B230215M10Rik;GAS 41;Glioma amplified sequence 41;Glioma-amplified sequence 41;NuBI-1;NuBI1;NuMA binding protein 1;NuMA-binding protein 1;Similar to the transcription factors AF9 and ENL;Weakly similar to M04B23;YAF 9;YEATS 4;YEATS domain containing protein 4;YETS4_HUMAN;OTTHUMP00000240879;OTTHUMP00000240880;OTTHUMP00000240882;glioma-amplified sequence-41
Recombinant Proteins
- Human
- Mouse
- Chicken
- Zebrafish
- E.coli
- Mammalian Cells
- HEK293
- GST
- His
- T7
- Non
- Myc&DDK
- His&Fc&Avi
Involved Pathway
YEATS4 involved in several pathways and played different roles in them. We selected most pathways YEATS4 participated on our site, such as C-MYB transcription factor network,Chromatin modifying enzymes,Chromatin organization, which may be useful for your reference. Also, other proteins which involved in the same pathway with YEATS4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| C-MYB transcription factor network | ADA,TOM1,LECT2,COL1A2,PPID,CSF1R,CREBBP,ADORA2B,GATA1,CDK6 |
| Chromatin organization | KDM6AL,KAT6B,RBBP4,BRPF1,MBD3B,VPS72,CSRP2BP,PADI3,SMYD2A,KDM3A |
| HATs acetylate histones | ELP4,KIAA1267,ENY2,SAP130,ING5,ELP2,BRPF1,BRPF3,ZZZ3,KANSL3 |
| Chromatin modifying enzymes | MSL2A,PRDM16,KDM6AL,KDM3A,KDM5A,BRD1,KDM6B,CHD4,KANSL3,ATXN7L3 |
Protein Function
YEATS4 has several biochemical functions, for example, DNA binding,protein C-terminus binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by YEATS4 itself. We selected most functions YEATS4 had, and list some proteins which have the same functions with YEATS4. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| DNA binding | FBXL19,TP63,TRIM16,EMX3,SS18L1,POU2AF1,NPAS1,MIER3,NR1D4A,FOXO6 |
| protein binding | HFE,S100A6,ALCAM,HIPK4,RPL15,MRPL12,GBAS,INADL,Tnfrsf22,POLE3 |
| transcription factor activity, sequence-specific DNA binding | ZNF323,ARID4A,UBN2B,RBPJA,ZNF16,ZNF500,ZNF45,NFYB,ZNF165,NFIL3-2 |
| structural constituent of cytoskeleton | ARPC3,NGS,EPB41L4B,KRT20,TUBA8L4,SORBS3,ACTR3,LOR,F-KER,SPTA1 |
| protein C-terminus binding | CTBP1,NCL,ERBB2,TAX1BP3,SIAH1A,PABPC1,EP300,VTA1,PEX5,KCNJ11 |
Interacting Protein
YEATS4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with YEATS4 here. Most of them are supplied by our site. Hope this information will be useful for your research of YEATS4.
MRGBP;ZNHIT1;TACC1;ACTL6A;VPS72
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