XPNPEP1
-
Official Full Name
X-prolyl aminopeptidase (aminopeptidase P) 1, soluble -
Overview
This gene encodes the cytosolic form of a metalloaminopeptidase that catalyzes the cleavage of the N-terminal amino acid adjacent to a proline residue. The gene product may play a role in degradation and maturation of tachykinins, neuropeptides, and peptide hormones. Alternative splicing results in multiple transcript variants. -
Synonyms
XPNPEP1;X-prolyl aminopeptidase (aminopeptidase P) 1, soluble;X prolyl aminopeptidase (aminopeptidase P) like , XPNPEP, XPNPEPL, XPNPEPL1;xaa-Pro aminopeptidase 1;Aminoacylproline aminopeptidase;Cytosolic aminopeptidase P;Soluble aminopeptidase P;soluble;X Pro aminopeptidase 1;X prolyl aminopeptidase 1 soluble;aminopeptidase P, cytosolic;APP1;RP11 451M19.1;SAMP;X prolyl aminopeptidase (aminopeptidase P) 1;X prolyl aminopeptidase (Aminopeptidase P) 1 soluble;X prolyl aminopeptidase 1;X-Pro aminopeptidase 1;X-prolyl aminopeptidase 1;Xaa Pro aminopeptidase 1;XPNPEP 1;XPNPEP;XPNPEPL;XPNPEPL1;XPP1_HUMAN;X-prolyl aminopeptidase 1, soluble
Recombinant Proteins
- Mouse
- Human
- Zebrafish
- Rhesus macaque
- Rat
- HEK293
- E.coli
- Mammalian Cell
- HEK293T
- Flag
- His
- T7
- Non
- His&SUMO
- His&Fc&Avi
- Myc&DDK
Involved Pathway
XPNPEP1 involved in several pathways and played different roles in them. We selected most pathways XPNPEP1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with XPNPEP1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
XPNPEP1 has several biochemical functions, for example, aminopeptidase activity,manganese ion binding,metalloaminopeptidase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by XPNPEP1 itself. We selected most functions XPNPEP1 had, and list some proteins which have the same functions with XPNPEP1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| aminopeptidase activity | ANPEP,NPEPPS,BLMH,METAP2B,ERAP1,DNPEP,ERAP2,TPP2,CTSL2,TRHDE |
| manganese ion binding | GALNT3,MPPE1,GALNT2,PRIMPOL,SOD2,PPM1M,LARGE,PPM1AB,LAP3,FAM20C |
| protein homodimerization activity | KCNE2,CHKA,GRM6,XDH,PYCARD,BMP7A,CITED1,UGT1A3,NR0B1,SPATA24 |
| metalloaminopeptidase activity | LNPEP,Npepo,RNPEPL1,METAP2B,METAP2A,LTA4H,ANPEP,TRHDE,ERAP2,ANPEPA |
Interacting Protein
XPNPEP1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with XPNPEP1 here. Most of them are supplied by our site. Hope this information will be useful for your research of XPNPEP1.
NUDT3;MAPK9;GSK3B;UBE2D3;POLA2;RINT1;DISC1
Resources
Related Services
Related Products
References
- Lopez, LM; Hill, WD; et al. Genes From a Translational Analysis Support a Multifactorial Nature of White Matter Hyperintensities. STROKE 46:341-347(2015).
- Xu, J; Cai, RX; et al. Genetic regulatory network analysis reveals that low density lipoprotein receptor-related protein 11 is involved in stress responses in mice. PSYCHIATRY RESEARCH 220:1131-1137(2014).
