USP21

  • Official Full Name

    ubiquitin-specific protease

  • Overview

    This gene encodes a member of the C19 peptidase family, also known as family 2 of ubiquitin carboxy-terminal hydrolases. The encoded protein cleaves ubiquitin from ubiquitinated proteins for recycling in intracellular protein degradation. The encoded protein is also able to release NEDD8, a ubiquitin-like protein, from NEDD8-conjugated proteins. This gene has been referred to as USP16 and USP23 but is now known as USP21. Alternatively spliced transcript variants have been described.

  • Synonyms

    USP21;ubiquitin-specific protease

Recombinant Proteins

  • Human
  • Rat
  • Mouse
  • E.coli
  • Mammalian Cell
  • HEK293
  • Mammalian cells
  • HEK293T
  • GST
  • His&SUMO
  • His
  • Non
  • Flag
  • Myc&DDK
  • His&Fc&Avi

    Involved Pathway

    USP21 involved in several pathways and played different roles in them. We selected most pathways USP21 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with USP21 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein

    Protein Function

    USP21 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by USP21 itself. We selected most functions USP21 had, and list some proteins which have the same functions with USP21. You can find most of the proteins on our site.

    Function Related Protein

    Interacting Protein

    USP21 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with USP21 here. Most of them are supplied by our site. Hope this information will be useful for your research of USP21.

    Resources

    References

    • Collaud, S; Tischler, V; et al. Lung neuroendocrine tumors: correlation of ubiquitinylation and sumoylation with nucleo-cytosolic partitioning of PTEN. BMC CANCER 15:-(2015).
    • Chao, M; Wang, HN; et al. The V-val subtype Epstein-Barr virus nuclear antigen 1 promotes cell survival after serum withdrawal. ONCOLOGY REPORTS 33:958-966(2015).

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    Q&As

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