UQCRH
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Official Full Name
ubiquinol-cytochrome c reductase hinge protein -
Overview
Cytochrome b-c1 complex subunit 6, mitochondrial is a protein that in humans is encoded by the UQCRH gene. -
Synonyms
UQCRH;ubiquinol-cytochrome c reductase hinge protein;cytochrome b-c1 complex subunit 6, mitochondrial;QCR6;ubiquinol cytochrome c reductase;complex III subunit VIII;UQCR8;Complex III subunit 6;Cytochrome b c1 complex subunit 6;Cytochrome b c1 complex subunit 6 mitochondrial;Cytochrome c1 non heme 11 kDa protein;MGC111572;Mitochondrial hinge protein;QCR 6;Ubiquinol cytochrome c reductase complex 11 kDa protein;Ubiquinol cytochrome c reductase complex 11 kDa protein mitochondrial;Ubiquinol cytochrome c reductase hinge protein;cytochrome c1 non-heme 11 kDa protein;ubiquinol-cytochrome c reductase complex 11 kDa protein;ubiquinol-cytochrome c reductase, complex III subunit VIII
Recombinant Proteins
- Human
- Zebrafish
- Chicken
- Rhesus macaque
- Rat
- Mouse
- E.coli
- Mammalian Cell
- HEK293
- HEK293T
- GST
- His
- Non
- His&Fc&Avi
- Myc&DDK
Involved Pathway
UQCRH involved in several pathways and played different roles in them. We selected most pathways UQCRH participated on our site, such as Oxidative phosphorylation,Metabolic pathways,Cardiac muscle contraction, which may be useful for your reference. Also, other proteins which involved in the same pathway with UQCRH were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Non-alcoholic fatty liver disease (NAFLD) | CASP7,COX6B2,NDUFA10,COX6A2,ADIPOQ,PIK3R1,NDUFV1,NDUFA13,ATF4,XBP1 |
| Cardiac muscle contraction | CACNB3,CACNA2D3,COX6C,ATP1B1B,CACNB3A,COX8C,ATP1B3,TNNT2A,ATP2A2,TNNC1B |
| Parkinsons disease | UQCR10,UCHL1,COX7B,NDUFA3,TH,NDUFV2,ATP5C1,ATP5G1,NDUFA4,ATP5F1 |
| Alzheimers disease | PPP3CA,EIF2AK3,TNF,GAPDH,CASP9,ATP5G3,LPL,COX8C,FAS,COX6C |
| Huntingtons disease | COX5A,SLC25A6,UQCRFS1,VDAC3,NDUFB5,PLCB3,UQCR10,CREB3L1,BDNF,SIN3A |
| Oxidative phosphorylation | NDUFB11,Atp5g2,NDUFV3,MT-ND4,SDHD,NDUFS8,NDUFS4,ctaG,UQCRB,COX10 |
| Metabolic pathways | ACSL1A,CS,ATP6V1G2,SGSH,GULO,DAO.3,ITPKC,AK7,FUT1,GUSB |
Protein Function
UQCRH has several biochemical functions, for example, protein binding,ubiquinol-cytochrome-c reductase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by UQCRH itself. We selected most functions UQCRH had, and list some proteins which have the same functions with UQCRH. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | GABARAP,RAD9,RLTPR,NFATC4,TUBA1C,TMBIM6,TFB1M,PEBP1,CCDC64B,ZBED4 |
| ubiquinol-cytochrome-c reductase activity | UQCRC1,UQCR11,UQCRQ,UQCRFS1,UQCR10 |
Interacting Protein
UQCRH has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with UQCRH here. Most of them are supplied by our site. Hope this information will be useful for your research of UQCRH.
ARL8A;FAM189B;RNF24;SIRT3;NPM1;HTT;NDUFA12
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References
- Berry, EA; De Bari, H; et al. Unanswered questions about the structure of cytochrome bc(1) complexes. BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS 1827:1258-1277(2013).
- Ye, RS; Pan, HB; et al. Molecular characterization and tissue expression profile of three novel ovine genes: ATP5O, NDUFA12 and UQCRH from muscle full-length cDNA library of black-boned sheep. MOLECULAR BIOLOGY REPORTS 39:5767-5774(2012).
