UNC5A
-
Official Full Name
unc-5 homolog A (C. elegans) -
Overview
UNC5A belongs to a family of netrin-1 (MIM 601614) receptors thought to mediate the chemorepulsive effect of netrin-1 on specific axons. For more information on UNC5 proteins, see UNC5C. -
Synonyms
UNC5H1
Recombinant Proteins
- Rat
- Human
- Mouse
- Zebrafish
- Mammalian cells
- Mammalian Cell
- CHO
- HEK293
- HEK293T
- Fc
- His
- Non
- His&Fc&Avi
- Myc&DDK
Involved Pathway
UNC5A involved in several pathways and played different roles in them. We selected most pathways UNC5A participated on our site, such as Axon guidance, which may be useful for your reference. Also, other proteins which involved in the same pathway with UNC5A were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Axon guidance | SPTBN2,FRS3,EPHA6,EPHA2,SPRED1,SEMA3AB,DAB2IPB,CSF2RA,SDCBP,EFNB2A |
Protein Function
UNC5A has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by UNC5A itself. We selected most functions UNC5A had, and list some proteins which have the same functions with UNC5A. You can find most of the proteins on our site.
| Function | Related Protein |
|---|
Interacting Protein
UNC5A has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with UNC5A here. Most of them are supplied by our site. Hope this information will be useful for your research of UNC5A.
Resources
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References
- Liu, D; Xiong, SQ; et al. Expression of netrin-1 receptors in retina of oxygen-induced retinopathy in mice. BMC OPHTHALMOLOGY 14:-(2014).
- Finci, LI; Kruger, N; et al. The Crystal Structure of Netrin-1 in Complex with DCC Reveals the Bifunctionality of Netrin-1 As a Guidance Cue. NEURON 83:839-849(2014).
