UBE2S
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Official Full Name
ubiquitin-conjugating enzyme E2S -
Overview
Protein ubiquitination requires the concerted action of the E1, E2, and E3 ubiquitin-conjugating enzymes. Ubiquitin is first activated through ATP-dependent formation of a thiol ester with ubiquitin-activating enzyme E1. The activated ubiquitin is then tr -
Synonyms
UBE2S;ubiquitin-conjugating enzyme E2S;ubiquitin-conjugating enzyme E2 S;E2 EPF;ubiquitin carrier protein;ubiquitin conjugating enzyme E2 24 kD;ubiquitin protein ligase;E2-EPF5;ubiquitin-protein ligase S;ubiquitin carrier protein S;ubiquitin-con
Recombinant Proteins
- Human
- Mouse
- Zebrafish
- Rhesus macaque
- Rat
- E.coli
- Mammalian Cell
- HEK293
- Insect Cell
- E. coli
- HEK293T
- GST
- His
- His&T7
- Non
- His&Strep
- His&Fc&Avi
- Myc&DDK
Involved Pathway
UBE2S involved in several pathways and played different roles in them. We selected most pathways UBE2S participated on our site, such as Ubiquitin mediated proteolysis, which may be useful for your reference. Also, other proteins which involved in the same pathway with UBE2S were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Ubiquitin mediated proteolysis | PIAS4,KLHL13,CUL1B,UBE2G1B,UBE2NB,UBE2D1B,UBE3C,UBE2KB,ANAPC7,PRPF19 |
Protein Function
UBE2S has several biochemical functions, for example, ATP binding,ubiquitin conjugating enzyme activity,ubiquitin protein ligase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by UBE2S itself. We selected most functions UBE2S had, and list some proteins which have the same functions with UBE2S. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| ubiquitin-protein transferase activity | XIAP,SHPRH,NHLRC1,UHRF1,FBXL14,ANKIB1A,RNF144AA,PDZRN3B,RNF182,UBE2E2 |
| ubiquitin protein ligase activity | CDC34,UBE3A,CMTM2A,HECTD2,FBXL22,UBE3C,RAG2,HECTD3,SIAH1A,HERC3 |
| ATP binding | MAPK8A,WARS2,ITPKB,CSNK1E,ACVR1L,IGF1RA,KIF19,AK7,PEBP1,PFTK1 |
| ubiquitin conjugating enzyme activity | UBE2E2,UBE2D2,CDC34,UBE2H,UBE2R2,UBE2G1,UBE2Z,UBE2O,UBE2D3,UBE2Q1 |
| contributes_to ubiquitin-protein transferase activity | KLHL10,BACH1,KLHL15,KEAP1A,KEAP1,DBN1,KEAP1B,KLHL9,KLHL23,CCIN |
| ubiquitin protein ligase binding | DTX1,PARK2,TMBIM6,XRCC5,UBE2A,RALB,SNX9,UBE2C,UBXN6,TRAF1 |
Interacting Protein
UBE2S has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with UBE2S here. Most of them are supplied by our site. Hope this information will be useful for your research of UBE2S.
UBE2V1;JTB;RBCK1;TNPO3;RNF40;p27958-pro_0000037566;P;USP6NL;ELMO3;CDC5L;RUSC1
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