SYNE2
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Official Full Name
spectrin repeat containing, nuclear envelope 2 -
Overview
The protein encoded by this gene is a nuclear outer membrane protein that binds cytoplasmic F-actin. This binding tethers the nucleus to the cytoskeleton and aids in the maintenance of the structural integrity of the nucleus. Several transcript variants encoding different isoforms have been found for this gene. -
Synonyms
SYNE2;spectrin repeat containing, nuclear envelope 2;nesprin-2;DKFZP434H2235;KIAA1011;Nesprin 2;NUA;NUANCE;SYNE 2;DKFZp686E01115;DKFZp686H1931;FLJ11014;FLJ43727;FLJ45710;FLJ46790;Nesprin2;Nuclear envelope spectrin repeat protein 2;Nucleus and actin connecting element;Nucleus and actin connecting element protein;Protein NUANCE;Spectrin repeat containing nuclear envelope 2;Synaptic nuclear envelope protein 2;Synaptic nuclei expressed gene 2;polytrophin;OTTHUMP00000179075;OTTHUMP00000245231;OTTHUMP00000245355;OTTHUMP00000245357;OTTHUMP00000245358;nucleus and acti;EDMD5;TROPH;SYNE-2
Recombinant Proteins
- Human
- Mouse
- E.coli
- Mammalian Cell
- HEK293T
- HEK293
- His
- Myc&DDK
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| SYNE2-376H | Recombinant Human SYNE2 Protein, His-tagged | E.coli | Human | His | Glu6~Gln296 | |
| SYNE2-16308M | Recombinant Mouse SYNE2 Protein | Mammalian Cell | Mouse | His |
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| SYNE2-1644H | Recombinant Human SYNE2 Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293T | Human | Myc&DDK |
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| SYNE2-3047H | Recombinant Human SYNE2 Protein, MYC/DDK-tagged | HEK293 | Human | Myc&DDK |
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| SYNE2-5767H | Recombinant Human SYNE2 Protein (Glu6-Ala264), His tagged | E.coli | Human | His | Glu6-Ala264 |
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| SYNE2-5768H | Recombinant Human SYNE2 Protein (Glu6-Asp263), N-His tagged | E.coli | Human | His | Glu6-Asp263 |
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| SYNE2-8910M | Recombinant Mouse SYNE2 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| SYNE2-8910M-B | Recombinant Mouse SYNE2 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
SYNE2 involved in several pathways and played different roles in them. We selected most pathways SYNE2 participated on our site, such as Meiotic Synapsis,Mus musculus biological processes,Ovarian Infertility Genes, which may be useful for your reference. Also, other proteins which involved in the same pathway with SYNE2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Ovarian Infertility Genes | DAZL,ZP2,NR5A1,MSH5,INHA,NRIP1,GJA4,ZP3,DMC1 |
| Meiotic synapsis | STAG1,POT1A,TEX12,ACD,SUN2,FKBP6,TINF2,TERF2,SYCP2,TERF2IP |
| Mus musculus biological processes | SYCE2,KLF5,MED11,POT1A,SYCP1,SUN2 |
Protein Function
SYNE2 has several biochemical functions, for example, actin binding,actin filament binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SYNE2 itself. We selected most functions SYNE2 had, and list some proteins which have the same functions with SYNE2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| actin binding | CALD1B,MYO1H,CCDC88A,WAS,CNN3B,MYHC4,MYLK,CFL2L,EZRB,WASF3 |
| actin filament binding | FSCN3,JUB,ADSSL1,USH1C,FSCN1A,PLDN,WIPF1,CTNNA2,PICK1,SHROOM2 |
Interacting Protein
SYNE2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SYNE2 here. Most of them are supplied by our site. Hope this information will be useful for your research of SYNE2.
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