SRSF7
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Official Full Name
serine/arginine-rich splicing factor 7 -
Overview
The protein encoded by this gene is a member of the serine/arginine (SR)-rich family of pre-mRNA splicing factors, which constitute part of the spliceosome. Each of these factors contains an RNA recognition motif (RRM) for binding RNA and an RS domain for binding other proteins. The RS domain is rich in serine and arginine residues and facilitates interaction between different SR splicing factors. In addition to being critical for mRNA splicing, the SR proteins have also been shown to be involved in mRNA export from the nucleus and in translation. Two transcript variants encoding different isoforms have been found for this gene. -
Synonyms
SRSF7;serine/arginine-rich splicing factor 7;SFRS7, splicing factor, arginine/serine rich 7 (35kD) , splicing factor, arginine/serine rich 7, 35kDa;9G8;AAG3;HSSG1;RBM37;SR splicing factor 7;ZCCHC20;ZCRB2;splicing factor 9G8;aging-associated p
Recombinant Proteins
- Human
- Chicken
- Rhesus macaque
- E.coli
- Mammalian Cell
- HEK293
- GST
- His
- Non
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| SRSF7-21H | Recombinant Human SRSF7 protein, GST-tagged | E.coli | Human | GST | 1-238 a.a. | |
| SRSF7-3019C | Recombinant Chicken SRSF7 | Mammalian Cell | Chicken | His |
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| SRSF7-4477R | Recombinant Rhesus monkey SRSF7 Protein, His-tagged | Mammalian Cell | Rhesus macaque | His |
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| SRSF7-1902HCL | Recombinant Human SFRS7 293 Cell Lysate | HEK293 | Human | Non |
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| SRSF7-22H | Recombinant Human SRSF7 protein, His-tagged | E.coli | Human | His | 1-238 aa |
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| SRSF7-4293R | Recombinant Rhesus Macaque SRSF7 Protein, His (Fc)-Avi-tagged | HEK293 | Rhesus macaque | His&Fc&Avi |
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| SRSF7-4293R-B | Recombinant Rhesus Macaque SRSF7 Protein Pre-coupled Magnetic Beads | HEK293 | Rhesus macaque |
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Involved Pathway
SRSF7 involved in several pathways and played different roles in them. We selected most pathways SRSF7 participated on our site, such as Spliceosome,Herpes simplex infection, which may be useful for your reference. Also, other proteins which involved in the same pathway with SRSF7 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Spliceosome | HNRPKL,HNRPK,SRSF3,PRPF8,SNW1,HSPA1A,NHP2L1A,CCDC12,DDX23,SNRNP27 |
| Herpes simplex infection | CLOCKA,HLA-DRB4,TYK2,OAS2,STAT1B,IL1B,HLA-DRB5,TRAF1,SRSF7A,C3A.1 |
Protein Function
SRSF7 has several biochemical functions, for example, nucleotide binding,poly(A) RNA binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SRSF7 itself. We selected most functions SRSF7 had, and list some proteins which have the same functions with SRSF7. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| zinc ion binding | QTRTD1,CPA6,ADAMTS8,TRIM47,LNX2,PHF10,USP44,MUL1A,RNF150,ZEB1 |
| protein binding | FARSA,MAP4K1,GAL,RBL1,IL18R1,MAGOHB,BACH1,EREG,PDZD7,ARHGEF15 |
| poly(A) RNA binding | H2-Q10,FAM50A,ANKRD17,THRAP3,RPS26,RBM28,HRSP12,SKIV2L2,EIF2S1B,DHX34 |
| nucleotide binding | ACVR1L,TTLL13,HNRNPAB,CAMKK1B,ACTB2,ACTA1A,DNM3A,SETD1BA,RBM4.1,ARF6B |
Interacting Protein
SRSF7 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SRSF7 here. Most of them are supplied by our site. Hope this information will be useful for your research of SRSF7.
NXF1;SDCBP;LUC7L2;RBBP6;SRPK2;SRPK1;Srek1
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References
- Robard, C; Daviau, A; et al. Phosphorylation status of the Kep1 protein alters its affinity for its protein binding partner alternative splicing factor ASF/SF2. BIOCHEMICAL JOURNAL 400:91-97(2006).
