SPEG
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Official Full Name
SPEG complex locus -
Overview
This gene encodes a protein with similarity to members of the myosin light chain kinase family. This protein family is required for myocyte cytoskeletal development. Studies in mouse have determined that a lack of this protein affected myocardial development. Multiple alternatively spliced transcript variants have been reported for this gene, but the full-length nature of only two variants that encode different protein isoforms has been defined. -
Synonyms
SPEG;SPEG complex locus;aortic preferentially expressed gene 1 , APEG1;striated muscle preferentially expressed protein kinase;BPEG;KIAA1297;MGC12676;SPEGalpha;SPEGbeta;Aortic preferentially expressed gene 1;Aortic preferentially expressed protein 1;APEG 1;Nuclear protein marker for differentiated aortic smooth muscle and down regulated with vascular injury;nuclear protein, marker for differentiated aortic smooth muscle and down-regulated with vascular injury;APEG1;APEG-1
Recombinant Proteins
- Human
- Mouse
- Zebrafish
- Rat
- E.coli
- Wheat Germ
- Mammalian Cell
- In Vitro Cell Free System
- HEK293
- GST
- His
- Non
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| SPEG-2912H | Recombinant Human SPEG, GST-tagged | E.coli | Human | GST | 851-964aa | |
| APEG1-675H | Recombinant Human APEG1 protein, GST-tagged | Wheat Germ | Human | GST |
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| SPEG-15868M | Recombinant Mouse SPEG Protein | Mammalian Cell | Mouse | His |
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| SPEG-1639Z | Recombinant Zebrafish SPEG | Mammalian Cell | Zebrafish | His |
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| SPEG-3797H | Recombinant Human SPEG protein, His-tagged | E.coli | Human | His | Met1-Glu113 |
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| SPEG-5700R | Recombinant Rat SPEG Protein | Mammalian Cell | Rat | His |
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| SPEG-1680HCL | Recombinant Human SPEG cell lysate | Human | Non |
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| SPEG-1118HF | Recombinant Full Length Human SPEG Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 113 amino acids |
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| SPEG-3520H | Recombinant Human SPEG protein, GST-tagged | E.coli | Human | GST | 1-113aa |
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| SPEG-5359R | Recombinant Rat SPEG Protein, His (Fc)-Avi-tagged | HEK293 | Rat | His&Fc&Avi |
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| SPEG-5359R-B | Recombinant Rat SPEG Protein Pre-coupled Magnetic Beads | HEK293 | Rat |
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| SPEG-8636M | Recombinant Mouse SPEG Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| SPEG-8636M-B | Recombinant Mouse SPEG Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
SPEG involved in several pathways and played different roles in them. We selected most pathways SPEG participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with SPEG were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
SPEG has several biochemical functions, for example, ATP binding,protein binding,protein serine/threonine kinase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by SPEG itself. We selected most functions SPEG had, and list some proteins which have the same functions with SPEG. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | NR5A2,HELZ,DHX15,SPOP,KIAA1737,TRIM5,RORC,IPO11,KIF4A,LAT2 |
| protein serine/threonine kinase activity | ROCK2,SGK2,SYK,STK35,MAPK12,PKN1,LIMK1,RPS6KA1,MAPK8,BCKDK |
| ATP binding | NLRX1,GALK1,IRAK1,CAMKK1A,MARS2,ABCA3,EHD2,TRPV1,MCCC2,FIGNL1 |
Interacting Protein
SPEG has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SPEG here. Most of them are supplied by our site. Hope this information will be useful for your research of SPEG.
PRMT1;czc8004;linkable pd173955 analogue;bosutinib;imatinib;MYC
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