SPCS1
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Official Full Name
signal peptidase complex subunit 1 homolog -
Synonyms
SPCS1;signal peptidase complex subunit 1 homolog (S. cerevisiae);signal peptidase complex subunit 1;HSPC033;SPC1;SPC12;YJR010C A;SPase 12 kDa subunit;signal peptidase 12kDa;microsomal signal peptidase 12 kDa subunit;YJR010C-A
Recombinant Proteins
- Human
- Mouse
- Zebrafish
- Chicken
- Sus scrofa (Pig)
- Dictyostelium Discoideum
- Pongo Abelii
- Bovine
- E.coli
- Mammalian Cell
- HEK293
- E.coli expression system
- HEK293T
- GST
- His
- Non
- Myc&DDK
- His&Fc&Avi
Involved Pathway
SPCS1 involved in several pathways and played different roles in them. We selected most pathways SPCS1 participated on our site, such as Protein export, which may be useful for your reference. Also, other proteins which involved in the same pathway with SPCS1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Protein export | SLC38A8,ARXES2,SEC61A1,HSPA5,SRP72,SEC11A,ARXES1,SEC62,SEC61G,SRP54 |
Protein Function
SPCS1 has several biochemical functions, for example, molecular_function,peptidase activity,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SPCS1 itself. We selected most functions SPCS1 had, and list some proteins which have the same functions with SPCS1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| molecular_function | ARHGAP22,C8orf42,TMEM263,LHFPL2,LYRM5B,ZFAND5,PORCNL,CRYBA1A,PCNXL2,DHRS7B |
| peptidase activity | GZME,FURIN,CASP3A,NPEPPS,PM20D1.1,MMP13A,REN2,GM5077,PAPPAB,GZMF |
| protein binding | HDAC4,RAB23,PSMB2,FCGR1A,ITGA3,RAB11A,SNRPE,GRAP2,CBFA2T3,GABPB1 |
Interacting Protein
SPCS1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SPCS1 here. Most of them are supplied by our site. Hope this information will be useful for your research of SPCS1.
q99ib8-pro_0000045598;q99ib8-pro_0000045596;q99ib8-pro_0000045597
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References
- Wolfe, MS; et al. Toward the structure of presenilin/gamma-secretase and presenilin homologs. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES 1828:2886-2897(2013).
- Krishnaswamy, S; Verdile, G; et al. The structure and function of Alzheimer's gamma secretase enzyme complex. CRITICAL REVIEWS IN CLINICAL LABORATORY SCIENCES 46:282-301(2009).
