SLC7A1
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Official Full Name
solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 -
Overview
High-affinity, low capacity permease involved in the transport of the cationic amino acids (arginine, lysine and ornithine) in non-hepatic tissues. May also function as an ecotropic retroviral leukemia receptor. -
Synonyms
SLC7A1;solute carrier family 7 (cationic amino acid transporter, y+ system), member 1;ERR;ATRC1;CAT-1;HCAT1;REC1L;high affinity cationic amino acid transporter 1;CAT1;ecotropic retroviral receptor;solute carrier family 7 member 1;amino acid transporter, cationic 1;ecotropic retrovirus receptor homolog;system Y+ basic amino acid transporter;ecotropic retroviral leukemia receptor homolog
Recombinant Proteins
- Human
- Mouse
- Chicken
- Rhesus macaque
- Rat
- E.coli
- Mammalian Cell
- Wheat Germ
- HEK293
- HEK293T
- His
- Non
- Myc&DDK
- His&Fc&Avi
Involved Pathway
SLC7A1 involved in several pathways and played different roles in them. We selected most pathways SLC7A1 participated on our site, such as MicroRNAs in cancer, which may be useful for your reference. Also, other proteins which involved in the same pathway with SLC7A1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| MicroRNAs in cancer | FOXP1,BCL2L2,CCNE1,MAP2K1,BMPR2,PRKCE,PIK3R2,ITGA5,RPTOR,CDCA5 |
Protein Function
SLC7A1 has several biochemical functions, for example, L-lysine transmembrane transporter activity,L-ornithine transmembrane transporter activity,antiporter activity. Some of the functions are cooperated with other proteins, some of the functions could acted by SLC7A1 itself. We selected most functions SLC7A1 had, and list some proteins which have the same functions with SLC7A1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | MCM2,EFCAB12,PML,MTNR1B,CUL4B,HBD,SAFB2,SLC7A11,VAPB,KIAA0947 |
| arginine transmembrane transporter activity | PQLC2,SLC7A3A,SLC7A4,SLC7A3 |
| antiporter activity | TMEM241,SLC8A1,SLC26A3.1,SLC7A7,SLC9A5,Slc4a2,SLC25A16,SLC35E2,CLCN4,SLC35E1 |
| L-lysine transmembrane transporter activity | SLC7A3,SLC7A2,PQLC2,SLC7A3A,SLC7A4 |
| L-ornithine transmembrane transporter activity | SLC7A4,SLC25A15,SLC7A3A,SLC7A3 |
Interacting Protein
SLC7A1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SLC7A1 here. Most of them are supplied by our site. Hope this information will be useful for your research of SLC7A1.
FATE1;b3xyc5_sollc;SLC33A1
Resources
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References
- Yang, JX; Tan, QS; et al. Cloning and molecular characterization of cationic amino acid transporter y(+)LAT1 in grass carp (Ctenopharyngodon idellus). FISH PHYSIOLOGY AND BIOCHEMISTRY 40:93-104(2014).
- Beyer, SR; Mallmann, RT; et al. Identification of Cysteine Residues in Human Cationic Amino Acid Transporter hCAT-2A That Are Targets for Inhibition by N-Ethylmaleimide. JOURNAL OF BIOLOGICAL CHEMISTRY 288:30411-30419(2013).
