SETBP1
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Official Full Name
SET binding protein 1 -
Overview
This gene encodes a protein which contains a several motifs including a ski homology region and a SET-binding region in addition to three nuclear localization signals. The encoded protein has been shown to bind the SET nuclear oncogene which is involved in DNA replication. Mutations in this gene are associated with Schinzel-Giedion midface retraction syndrome. Multiple transcript variants encoding different isoforms have been found for this gene. -
Synonyms
SETBP1;SET binding protein 1;SET-binding protein;KIAA0437;SEB;SETBP 1
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| SETBP1-1587HCL | Recombinant Human SETBP1 cell lysate | Human | Non |
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| SETBP1-2054H | Recombinant Human SETBP1 Protein, His&GST-tagged | E.coli | Human | His&GST | Gly1297-Pro1596 |
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| Setbp1-5798M | Recombinant Mouse Setbp1 Protein, Myc/DDK-tagged | HEK293T | Mouse | Myc&DDK |
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| SETBP1-6550H | Recombinant Human SETBP1 Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293T | Human | Myc&DDK |
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| SETBP1-996H | Recombinant Human SETBP1 Protein, MYC/DDK-tagged | HEK293 | Human | Myc&DDK |
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Involved Pathway
SETBP1 involved in several pathways and played different roles in them. We selected most pathways SETBP1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with SETBP1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
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Protein Function
SETBP1 has several biochemical functions, for example, DNA binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SETBP1 itself. We selected most functions SETBP1 had, and list some proteins which have the same functions with SETBP1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| DNA binding | ZNF227,SMYD1,SMAD9,ISL1L,ABI2,SIX9,H3F3B.1,BEND5,ZNF35,ZNF701 |
| protein binding | GGACT,KRTAP2-3,STRA13,PICALM,TRAPPC2,SIRT7,MTF1,CRHBP,PIK3CD,SH2B2 |
Interacting Protein
SETBP1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SETBP1 here. Most of them are supplied by our site. Hope this information will be useful for your research of SETBP1.
g2xkq0_human;UBE2I;YAF2;SPANXD;PLEKHF2;XAGE1A
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References
- Angeletti, D; Sandalova, T; et al. Binding of Subdomains 1/2 of PfEMP1-DBL1 alpha to Heparan Sulfate or Heparin Mediates Plasmodium falciparum Rosetting. PLOS ONE 10:-(2015).
- Kim, JT; Liu, CM; et al. Neurotensin, a novel target of Wnt/beta-catenin pathway, promotes growth of neuroendocrine tumor cells. INTERNATIONAL JOURNAL OF CANCER 136:1475-1481(2015).
