SEMG1
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Official Full Name
semenogelin I -
Overview
The protein encoded by this gene is the predominant protein in semen. The encoded secreted protein is involved in the formation of a gel matrix that encases ejaculated spermatozoa. The prostate-specific antigen (PSA) protease processes this protein into smaller peptides, with each possibly having a separate function. The proteolysis process breaks down the gel matrix and allows the spermatozoa to move more freely. -
Synonyms
SEMG1;semenogelin I;SEMG;semenogelin-1;cancer/testis antigen 103;CT103;semen coagulating protein;SGI;dJ172H20.2;FLJ78262;MGC14719
Recombinant Proteins
- Human
- E.coli
- HEK293
- Mammalian cells
- His
- His&SUMO
- Non
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| SEMG1-698H | Recombinant Human SEMG1 Protein, His-tagged | E.coli | Human | His | Gln24~Thr462 | |
| SEMG1-1368H | Recombinant Human SEMG1 Protein, His-SUMO-tagged | E.coli | Human | His&SUMO | 24-402 a.a. |
|
| SEMG1-221H | Recombinant Human SEMG1 Protein, His-tagged | HEK293 | Human | His |
|
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| SEMG1-7640H | Recombinant Human SEMG1, His-tagged | E.coli | Human | Non | 24-462aa |
|
| SEMG1-7760H | Recombinant Human SEMG1, His-tagged | HEK293 | Human | His |
|
|
| SEMG1-1977HCL | Recombinant Human SEMG1 293 Cell Lysate | HEK293 | Human | Non |
|
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| SEMG1-6262H | Recombinant Human SEMG1 Protein (Gln24-Thr402), C-His tagged | Mammalian cells | Human | His | Gln24-Thr402 |
|
Involved Pathway
SEMG1 involved in several pathways and played different roles in them. We selected most pathways SEMG1 participated on our site, such as Amyloid formation,Metabolism of proteins, which may be useful for your reference. Also, other proteins which involved in the same pathway with SEMG1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Amyloid formation | RHBDL1,NAT8,TGFBI,APCS,SAA1,MFGE8,ODAM,CST3,LTF,NAT8B |
| Metabolism of proteins | FBXW5,PFDN5,ST8SIA2,MUC5AC,MFGE8,TOMM6,FXC1,EID3,FURINB,NAPB |
Protein Function
SEMG1 has several biochemical functions, for example, metal ion binding,protein binding,structural molecule activity. Some of the functions are cooperated with other proteins, some of the functions could acted by SEMG1 itself. We selected most functions SEMG1 had, and list some proteins which have the same functions with SEMG1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| structural molecule activity | IFLTD1,CLDNB,CAV1,SEPT5,KRTAP3-2,KRT94,KRT81,CLDNG,ANK1,CLDN8 |
| metal ion binding | CYP2K17,PDE4C,TRIM46B,ZNF287,TRIM26,DNMT3A,DDAH1,CNDP2,ZDHHC13,ZKSCAN6 |
| protein binding | UBA5,NABP1,BTC,EFEMP1,TRAPPC4,EEF1E1,PRPF4B,SV2B,ROBO2,MSMB |
Interacting Protein
SEMG1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SEMG1 here. Most of them are supplied by our site. Hope this information will be useful for your research of SEMG1.
UBQLN4;PIK3R2;ESR1
Resources
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References
- O'Rand, MG; Widgren, EE; et al. Loss of Calcium in Human Spermatozoa via EPPIN, the Semenogelin Receptor. BIOLOGY OF REPRODUCTION 86:-(2012).
- Wang, ZJ; Widgren, EE; et al. Characterization of an Eppin protein complex from human semen and spermatozoa. BIOLOGY OF REPRODUCTION 77:476-484(2007).
