RUVBL2
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Official Full Name
RuvB-like 2 -
Synonyms
RUVBL2;RuvB-like 2 (E. coli);RuvB (E coli homolog) like 2;ruvB-like 2;ECP51;INO80 complex subunit J;INO80J;reptin;Reptin52;Rvb2;TIH2;TIP48;TIP49b;ECP-51;reptin 52;TAP54-beta;reptin52 protein;repressing pontin 52;RuvB (E coli homolo
Recombinant Proteins
- Human
- Rhesus macaque
- Zebrafish
- Mouse
- E.coli
- Wheat Germ
- Mammalian Cell
- HEK293
- HEK293T
- Mammalian cells
- His&SUMO
- His
- GST
- Non
- Myc&DDK
- Flag
- His&Fc&Avi
Involved Pathway
RUVBL2 involved in several pathways and played different roles in them. We selected most pathways RUVBL2 participated on our site, such as ATF-2 transcription factor network,C-MYC pathway,Cell Cycle, which may be useful for your reference. Also, other proteins which involved in the same pathway with RUVBL2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| ATF-2 transcription factor network | POU2F1,DUSP1,DUSP10,JUND,CSRP2,KCNA3,DDIT3,JUN,CREB1,GADD45A |
| Cell cycle | STAG2,DCTN1A,CENPJ,CTDNEP1A,HDAC5,APITD1,YWHABL,ORC3L,CENPH,CEP70 |
| Extension of Telomeres | WRAP53,DKC1 |
| Chromatin modifying enzymes | KDM3A,PRDM16,RBBP5,MTA1,KDM5BA,SMARCB1A,ASH2L,HIST2H3C,RBBP7,PADI4 |
| Chromosome Maintenance | CENPA,CENPC1,RBBP4,DNA2,PANE1,POT1A,ACD,ITGB3BP,CENPL,CENPP |
| HATs acetylate histones | MSL2A,KAT6A,MSL1,TADA2A,KIAA1267,ING4,KAT7A,ING5B,USP22,CAPNS2 |
| Chromatin organization | MSL2B,DMAP1,KDM5A,KDM1B,KAT7B,MSL2A,SMYD2A,SMARCB1,SMARCA2,EP400 |
| C-MYC pathway | ACTL6A,MYC,HBP1,KAT5 |
Protein Function
RUVBL2 has several biochemical functions, for example, ATP binding,ATP-dependent 5-3 DNA helicase activity,ATP-dependent DNA helicase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by RUVBL2 itself. We selected most functions RUVBL2 had, and list some proteins which have the same functions with RUVBL2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| ATP-dependent 5-3 DNA helicase activity | HELB,DOM3Z,NUDT19,PIF1,IGHMBP2 |
| protein binding | ACD,DULLARD,NAE1,CFL2,GP1BA,AGXT,RPN1,KIAA0408,MYL2,TAF1D |
| unfolded protein binding | DNAJB13,SYVN1,DNAJA2L,NAP1L4,HTRA2,DNAJB1A,CCT8,ERLEC1,DNAJB8,APCS |
| RNA polymerase II core promoter sequence-specific DNA binding | WBP2,SP1,SUZ12,HOXB3,SMAD5,SPI1,NSD1,SOX8,RUNX2,FOS |
| ATP-dependent DNA helicase activity | BRIP1,CHD1,FBXO18,CHD4,RTEL1,ERCC2,GTF2H4,XRCC6,DDX3X,WRN |
| RNA polymerase II distal enhancer sequence-specific DNA binding | SOX10,SFPI1,PROP1,MEOX2,GATA2,RELA,NFATC1,PAX4,NFE2L2,RXRB |
| ATP binding | AKT2L,SMC3,NTRK2B,RYK,SMARCAL1,MAT2AB,STYK1,SETX,AASDH,ABCD4 |
| DNA helicase activity | MCM5,MCM3L,DNA2,CHD8,RECQL,SUPV3L1,MCM6L,RUVBL1,MCM3,FBXO18 |
| chromatin DNA binding | MED1,MYOG,NKAP,PPARGC1A,H1F0,H2AFZ,THRB,NOTCH1,HIST1H1C,RARA |
Interacting Protein
RUVBL2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RUVBL2 here. Most of them are supplied by our site. Hope this information will be useful for your research of RUVBL2.
RUVBL1
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