RNMT
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Official Full Name
RNA (guanine-7-) methyltransferase -
Overview
Met, a high affinity tyrosine kinase receptor for hepatocyte growth factor (HGF, also known as scatter factor) is a disulfide-linked heterodimer made of 45 kDa alpha- and 145 kDa beta-subunits (1,2). The alpha-subunit and the amino-terminal region of the -
Synonyms
RNMT;RNA (guanine-7-) methyltransferase;mRNA cap guanine-N7 methyltransferase;RG7MT1;hMet;hCMT1;hcm1p;mRNA cap methyltransferase;mRNA (guanine-7-)methyltransferase;mRNA (guanine-N(7)-)-methyltransferase;MET;hCMT1c;KIAA0398;DKFZp686H1252
Recombinant Proteins
- Human
- Canine
- Mouse
- Zebrafish
- Rat
- Cynomolgus
- E.coli
- C-His
- Mammalian Cell
- Human
- HEK293
- HEK293T
- GST
- His
- Non
- Myc&DDK
- His&Fc&Avi
Involved Pathway
RNMT involved in several pathways and played different roles in them. We selected most pathways RNMT participated on our site, such as mRNA surveillance pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with RNMT were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| mRNA surveillance pathway | PABPN1,CPSF5,MSI1,PPP2R2D,DAZAP1,UPF1,HBS1L,PAPOLB,PABPC1B,ETF1 |
Protein Function
RNMT has several biochemical functions, for example, RNA binding,mRNA (guanine-N7-)-methyltransferase activity,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by RNMT itself. We selected most functions RNMT had, and list some proteins which have the same functions with RNMT. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | HIST2H4,HP1BP3,NUSAP1,DNMT3L,FAM107A,NOS3,TAF1C,RNF180,GLTP,MS4A12 |
| RNA binding | RPS3,THUMPD2,HNRPKL,LIN28A,CTIF,SFPI1,RBM8A,RPL30,SETD1B,RPL7A |
Interacting Protein
RNMT has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RNMT here. Most of them are supplied by our site. Hope this information will be useful for your research of RNMT.
ssrna_ug
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References
- Gonatopoulos-Pournatzis, T; Cowling, VH; et al. RAM function is dependent on Kap beta 2-mediated nuclear entry. BIOCHEMICAL JOURNAL 457:473-484(2014).
- Aregger, M; Cowling, VH; et al. Human cap methyltransferase (RNMT) N-terminal non-catalytic domain mediates recruitment to transcription initiation sites. BIOCHEMICAL JOURNAL 455:67-73(2013).
