RDBP
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Official Full Name
RD RNA binding protein -
Overview
The protein encoded by this gene is part of a complex termed negative elongation factor (NELF) which represses RNA polymerase II transcript elongation. This protein bears similarity to nuclear RNA-binding proteins; however, it has not been demonstrated that this protein binds RNA. The protein contains a tract of alternating basic and acidic residues, largely arginine (R) and aspartic acid (D). The gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. -
Synonyms
RDBP;RD RNA binding protein;negative elongation factor E;D6S45;NELF E;RD;RDP;nuclear protein;RD RNA-binding protein;RNA-binding protein RD;major histocompatibility complex gene RD;negative elongation factor polypeptide E;NELF-E
Recombinant Proteins
- Human
- Mouse
- E.coli
- Mammalian Cell
- HEK293
- His
- Non
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| RDBP-2235H | Recombinant Human RDBP, His-tagged | E.coli | Human | His | 1-333aa | |
| RDBP-14043M | Recombinant Mouse RDBP Protein | Mammalian Cell | Mouse | His |
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| RDBP-29223TH | Recombinant Human RDBP, His-tagged | E.coli | Human | His | 63-380 a.a. |
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| RDBP-29224TH | Recombinant Human RDBP, His-tagged | E.coli | Human | His | 380 amino acids |
|
| RDBP-3419H | Recombinant Human RD RNA Binding Protein, His-tagged | E.coli | Human | His |
|
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| RDBP-2440HCL | Recombinant Human RDBP 293 Cell Lysate | HEK293 | Human | Non |
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| RDBP-7505M | Recombinant Mouse RDBP Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| RDBP-7505M-B | Recombinant Mouse RDBP Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
RDBP involved in several pathways and played different roles in them. We selected most pathways RDBP participated on our site, such as Abortive elongation of HIV-1 transcript in the absence of Tat,Disease,Formation of HIV elongation complex in the absence of HIV Tat, which may be useful for your reference. Also, other proteins which involved in the same pathway with RDBP were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Disease | CUX1,TRIM24,TNKS2,STX1B,KPNA5,AP1G1,PSTPIP2,SUPT5H,KREMEN2,KPNA3 |
| Formation of HIV elongation complex in the absence of HIV Tat | ELL,TH1L,SSRP1,TCEA1,TCEB3,COBRA1,SUPT4H1,PSTPIP2,CTDP1,SUPT5H |
| Formation of HIV-1 elongation complex containing HIV-1 Tat | SUPT5H,SSRP1,CDK9,CTDP1,TH1L,COBRA1,SUPT4H1,TCEB3,ELL,WHSC2 |
| Formation of RNA Pol II elongation complex | COBRA1,PSTPIP2,SUPT4H1,CCNT2B,SSRP1A,SSRP1,CDK9,GM3258,SUPT16H,WHSC2 |
| Gene Expression | MAEL,FARSB,SF3B2,ZKSCAN3,SUZ12,TRMT61A,ZNF680,ZNF614,HNRNPA2B1,DDX6 |
| Formation of the Early Elongation Complex | SUPT5H,TH1L,WHSC2,COBRA1,CTDP1,SUPT4H1,GM3258,NELFE |
| Formation of the HIV-1 Early Elongation Complex | SUPT5H,CTDP1,COBRA1,TH1L,WHSC2,SUPT4H1 |
| Abortive elongation of HIV-1 transcript in the absence of Tat | SUPT4H1,TH1L,WHSC2,SUPT5H,CTDP1,COBRA1 |
Protein Function
RDBP has several biochemical functions, for example, RNA binding,chromatin binding,nucleotide binding. Some of the functions are cooperated with other proteins, some of the functions could acted by RDBP itself. We selected most functions RDBP had, and list some proteins which have the same functions with RDBP. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| poly(A) RNA binding | ANP32A,EIF4A3,NTPCR,NOP16,ERH,EIF3C,PKN2,C22orf28,CLK3,HERC5 |
| nucleotide binding | GRK7B,RPS24,EEF2B,cka1,PPARGC1A,SRSF1A,APLF,UBE2NA,ATP8B3,RALBB |
| chromatin binding | HIF1AB,NPM2,TOX,FABP1,CRX,NR5A5,YAP1,GATA5,WAC,SIRT6 |
| protein binding | CD46,PTGDR,SRRT,POLR3F,CBLL1,SOCS7,ANTXR1,ZNF433,OAS2,CCDC36 |
| RNA binding | WRAP53,CNOT4B,DUSP11,PPP5C,RTCA,UMPS,ADAD2,PSMA6,SARS,CSDC2 |
Interacting Protein
RDBP has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RDBP here. Most of them are supplied by our site. Hope this information will be useful for your research of RDBP.
NELFB;NELFA;TRIM27;CCDC57;MTUS2;NELFCD
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