RAB5C
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Official Full Name
RAB5C, member RAS oncogene family -
Overview
Ras-related protein Rab-5C is a protein that in humans is encoded by the RAB5C gene.RAB5C belongs to the Ras-related protein family. -
Synonyms
RAB5C;RAB5C, member RAS oncogene family;RABL;ras-related protein Rab-5C;RAB;member of RAS oncogene family like;member of RAS oncogene family;RAB5CL;RAB5C, member of RAS oncogene family;L1880;RAB5L;MGC117217;MGC138857
Recombinant Proteins
- Zebrafish
- Mouse
- Rhesus macaque
- Human
- Chicken
- Mammalian Cell
- E.coli
- HEK293
- HEK293T
- Mammalian cells
- His
- Non
- Myc&DDK
- GST
- His&Fc&Avi
- His&SUMO
- Flag
Involved Pathway
RAB5C involved in several pathways and played different roles in them. We selected most pathways RAB5C participated on our site, such as Ras signaling pathway,Endocytosis,Phagosome, which may be useful for your reference. Also, other proteins which involved in the same pathway with RAB5C were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Ras signaling pathway | CDC42,GNG4,GNB2,RAPGEF5,Pdgfa&Pdgfb,TEK,FGF7,MAPK3,GNG13,PLA2G4F |
| Phagosome | THBS1,TUBA7L,OLR1,ATP6V1C1A,NCF1,ATP6V1G1,MBL1,THBS4A,ATP6V0D1,DYNC1LI2 |
| Amoebiasis | C8A,C8B,PLCB3,MUC2,SERPINB1C,CD14,COL4A5,SERPINB1B,PIK3R1,COL5A2 |
| Tuberculosis | CARD9,Ifna11,IRAK4,IRAK2,RAB5B,CASP10,Casp3,IL10RB,NFKB1,TLR2 |
| Endocytosis | RAB11A,PLD1A,TFR1A,CHMP3,IL2RA,BIN1B,ARPC1A,WIPF1,CDC42,FAM21C |
Protein Function
RAB5C has several biochemical functions, for example, GDP binding,GTP binding,GTPase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by RAB5C itself. We selected most functions RAB5C had, and list some proteins which have the same functions with RAB5C. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| GTPase activity | RAB19,RAB1BA,GNA11,GNA15.4,TUBA1L2,RHOF,RALAA,DNM1,GNAI2B,GTPBP1L |
| GDP binding | RAB11B,RALB,RAP2B,MIEF1,RAB21,RHOB,RAB2A,RAB27B,EIF2B1,PCK1 |
| protein binding | NEDD8,GPR37L1,Tnfrsf23,TMEM203,C1orf116,MAVS,RAB27B,C7orf50,ESRP1,PLCE1 |
| GTP binding | RHOGD,MX2,ARL10,THG1L,RASD1,GNAI2A,AK4,RAB33B,GTPBP10,EHD2 |
Interacting Protein
RAB5C has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RAB5C here. Most of them are supplied by our site. Hope this information will be useful for your research of RAB5C.
RAB5A;APPL2;SUN2;VCAM1;1-phosphatidyl-1d-myo-inositol 3,5-bisphosphate;1-phosphatidyl-1d-myo-inositol 4,5-bisphosphate;EEA1;TGFBRAP1;EPB41
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References
- Tan, YS; Kim, M; et al. Regulation of RAB5C Is Important for the Growth Inhibitory Effects of MiR-509 in Human Precursor-B Acute Lymphoblastic Leukemia. PLOS ONE 9:-(2014).
