Pigf
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Official Full Name
phosphatidylinositol glycan anchor biosynthesis, class F -
Overview
This gene encodes a protein involved in glycosylphosphatidylinositol (GPI)-anchor biosynthesis. The GPI-anchor, a glycolipid containing three mannose molecules in its core backbone, is found on many blood cells where it serves to anchor proteins to the cell surface. The encoded protein and another GPI synthesis protein, PIGO, function in the transfer of ethanolaminephosphate to the third mannose in GPI. Alternatively spliced transcript variants encoding different isoforms have been described. -
Synonyms
PIGF;phosphatidylinositol glycan anchor biosynthesis, class F;phosphatidylinositol glycan, class F;phosphatidylinositol-glycan biosynthesis class F protein;PIG-F;GPI11 homolog;MGC32646;MGC33136
Recombinant Proteins
- Zebrafish
- Mouse
- Human
- Mus musculus
- Mammalian Cell
- E.coli
- HEK293
- E.coli expression system
- His
- Non
- Fc
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| PIGF-11676Z | Recombinant Zebrafish PIGF | Mammalian Cell | Zebrafish | His |
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| Pigf-330M | Recombinant Mouse Pigf | E.coli | Mouse | Non |
|
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| PIGF-456H | Recombinant Human PIGF | HEK293 | Human | Non |
|
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| PIGF-464H | Recombinant Human PIGF | Mammalian Cell | Human | His |
|
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| PIGF-1123H | Active Recombinant Human PIGF Protein, Fc-tagged | HEK293 | Human | Fc | 1-170 a.a. |
|
| PIGF-3854H | Recombinant Human PIGF Protein, His (Fc)-Avi-tagged | HEK293 | Human | His&Fc&Avi |
|
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| PIGF-3854H-B | Recombinant Human PIGF Protein Pre-coupled Magnetic Beads | HEK293 | Human |
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| RFL30949MF | Recombinant Full Length Mouse Phosphatidylinositol-Glycan Biosynthesis Class F Protein(Pigf) Protein, His-Tagged | E.coli expression system | Mus musculus | His | Full L. Full Length (1-219) |
|
Involved Pathway
Pigf involved in several pathways and played different roles in them. We selected most pathways Pigf participated on our site, such as Glycosylphosphatidylinositol(GPI)-anchor biosynthesis,Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with Pigf were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Metabolic pathways | HADH,ACAD8,Cel,GPAA1,GCDH,ST6GALNAC1,DOLK,NDUFAB1A,LIPT1,POLA1 |
| Glycosylphosphatidylinositol(GPI)-anchor biosynthesis | PIGV,PIGN,PIGQ,GPAA1,PIGW,PIGZ,PIGO,PIGL,PIGA,DPM2 |
Protein Function
Pigf has several biochemical functions, for example, ethanolaminephosphotransferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by Pigf itself. We selected most functions Pigf had, and list some proteins which have the same functions with Pigf. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| ethanolaminephosphotransferase activity | EPT1,CEPT1 |
Interacting Protein
Pigf has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Pigf here. Most of them are supplied by our site. Hope this information will be useful for your research of Pigf.
Resources
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References
- Penson, RT; Moore, KM; et al. A phase II study of ramucirumab (IMC-1121B) in the treatment of persistent or recurrent epithelial ovarian, fallopian tube or primary peritoneal carcinoma. GYNECOLOGIC ONCOLOGY 134:478-485(2014).
- Deissler, HL; Lang, GK; et al. Capacity of aflibercept to counteract VEGF-stimulated abnormal behavior of retinal microvascular endothelial cells. EXPERIMENTAL EYE RESEARCH 122:20-31(2014).
