PRSS3
-
Official Full Name
protease, serine, 3 -
Overview
This gene encodes a trypsinogen, which is a member of the trypsin family of serine proteases. This enzyme is expressed in the brain and pancreas and is resistant to common trypsin inhibitors. It is active on peptide linkages involving the carboxyl group of lysine or arginine. This gene is localized to the locus of T cell receptor beta variable orphans on chromosome 9. Four transcript variants encoding different isoforms have been described for this gene. -
Synonyms
PRSS3;protease, serine, 3;protease, serine, 3 (mesotrypsin) , protease, serine, 4 (trypsin 4, brain) , PRSS4;trypsin-3;mesotrypsin;TRY3;TRY4;Brain trypsinogen;Mesotrypsinogen;MTG;Pancreatic trypsinogen III;Protease, serine, 4 (trypsin 4, brain);PRSS4;Serine protease 3;Serine protease 4;T9;TRY3_HUMAN;Trypsin 3;Trypsin III;Trypsin IV;Trypsinogen 4;Trypsinogen 5;Trypsinogen IV
Recombinant Proteins
- Human
- Mouse
- Rat
- Chicken
- HEK293
- Mammalian cells
- E.coli
- Insect Cell
- Mammalian Cell
- Human Cell
- HEK293T
- His
- His&T7
- Non
- His&Fc&Avi
Involved Pathway
PRSS3 involved in several pathways and played different roles in them. We selected most pathways PRSS3 participated on our site, such as Neuroactive ligand-receptor interaction,Pancreatic secretion,Protein digestion and absorption, which may be useful for your reference. Also, other proteins which involved in the same pathway with PRSS3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Neuroactive ligand-receptor interaction | Gh,TAAR14G,HTR6,MC1R,TAAR8C,BDKRB2,MLNR,GABRR1,P2RX4,TAAR7F |
| Influenza A | PRSS1,RSAD2,AKT1,NFKB1,KPNA2,PIK3R3,DNAJC3,PIK3CG,IL18,IFIH1 |
| Protein digestion and absorption | SLC7A7,CELA3A,COL15A1,COL24A1,CELA2B,SLC16A10,KCNK5,ATP1B3,LOC780933,COL6A5 |
| Pancreatic secretion | Car2,ATP1A3,Cel,PNLIPRP2,SLC4A4,ATP1B4,AMY2A,ITPR3,RAP1B,KCNQ1 |
Protein Function
PRSS3 has several biochemical functions, for example, calcium ion binding,protein binding,serine-type endopeptidase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by PRSS3 itself. We selected most functions PRSS3 had, and list some proteins which have the same functions with PRSS3. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| calcium ion binding | SERPINB1A,EFCC1,CALB2B,MBL2,LOC100686744,AP1S2,PCDH2G10,SYT11A,NECAB2,CAPN2L |
| protein binding | MAD2L1BP,RAB3B,ZNF239,CDCA5,PER2,CST9L,RPL15,DMKN,TNF,SMPDL3A |
| serine-type endopeptidase activity | KLK2,F10,ELA2,EGFBP2,F2,KLK1B11,GZMK,TYSND1,DPP4,APEH |
| serine-type peptidase activity | GZMM,HTRA3,TMPRSS4B,KLK1B24,HTRA2,PLAUB,PRSS12,DPP8,KLK1B3,GM5077 |
Interacting Protein
PRSS3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PRSS3 here. Most of them are supplied by our site. Hope this information will be useful for your research of PRSS3.
PSAP;CASP14;chi36;IGHA1;ALB;SHC1
Resources
Related Services
Related Products
References
