PPME1
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Official Full Name
protein phosphatase methylesterase 1 -
Overview
Protein phosphatase methylesterase-1 catalyzes the demethylation of the protein phosphatase-2A catalytic subunit;(PPP2CA; MIM 176915) (Ogris et al., 1999 (PubMed 10318862)). -
Synonyms
PPME1;protein phosphatase methylesterase 1;PME 1;PME-1;PME1;PPME1_HUMAN;protein phosphatase methylesterase-1
Recombinant Proteins
- Human
- Zebrafish
- Mouse
- Chicken
- Rhesus macaque
- Rat
- E.coli
- Mammalian Cell
- Insect Cell
- HEK293
- HEK293T
- GST
- His
- Non
- His&Fc&Avi
- Myc&DDK
Involved Pathway
PPME1 involved in several pathways and played different roles in them. We selected most pathways PPME1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with PPME1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
PPME1 has several biochemical functions, for example, protein C-terminal methylesterase activity,protein kinase binding,protein phosphatase 2A binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PPME1 itself. We selected most functions PPME1 had, and list some proteins which have the same functions with PPME1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein kinase binding | TBC1D14,FBXO7,RAD9,PTPRR,PTPN1,AP1B1,SLC12A7,PRKACA,PAK2,CHEK2 |
| protein phosphatase 2A binding | SHC1,STRN,PTPN1,MAPT,RPS6KB1,HMGCR,PPP2R2A,AKT1,ARPP19,EIF4EBP1 |
| protein phosphatase inhibitor activity | PPP1R35,PHACTR3,PPP1R1C,SH3RF2,PPP1R36,PPP1R14C,PPP1R2P3,ENSA,LMTK2,GLC8 |
| protein phosphatase type 2A regulator activity | PPP2R2C,PPP2R5B,PPP2R2A,PPP2R2B,PPP2R5D,PPP2R2CA,PPP2R1A,EIF2AK2,PPP2R4,pab1 |
| protein phosphatase binding | IRS2,PPP6R1,AP3B1,NEK2,EGFR,ANAPC5,STAT3,FGF19,MVP,LCK |
Interacting Protein
PPME1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PPME1 here. Most of them are supplied by our site. Hope this information will be useful for your research of PPME1.
PPP2R1A;PPP2CA;ETS1;Ppp2r1a;TFAP2A;PPP2CB
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