PHEX
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Official Full Name
phosphate regulating endopeptidase homolog, X-linked -
Synonyms
PHEX;phosphate regulating endopeptidase homolog, X-linked;HPDR, HYP, phosphate regulating gene with homologies to endopeptidases on the X chromosome (hypophosphatemia, vitamin D resistant rickets);phosphate-regulating neutral endopeptidase;HPDR1;HYP1;PEX;XLH;metalloendopeptidase homolog PEX;X-linked hypophosphatemia protein;vitamin D-resistant hypophosphatemic rickets protein;phosphate regulating gene with homologies to endopeptidases on the X chromosome (hypophosphatemia, vitamin D resistant rickets);HYP;HPDR;LXHR
Recombinant Proteins
- Human
- Mouse
- Chicken
- Zebrafish
- Mus musculus
- E.coli
- Sf21 Cells
- Mammalian Cells
- HEK293
- His
- Non
- His&Fc&Avi
Involved Pathway
PHEX involved in several pathways and played different roles in them. We selected most pathways PHEX participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with PHEX were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
PHEX has several biochemical functions, for example, aminopeptidase activity,metalloendopeptidase activity,zinc ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PHEX itself. We selected most functions PHEX had, and list some proteins which have the same functions with PHEX. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| aminopeptidase activity | TRHDE,PEPD,ANPEP,METAP2A,NPEPPS,RNPEP,LAP3,LTA4H,CTSH,METAP1 |
| zinc ion binding | PHC2A,MEX3B,PDLIM4,MMP1,ZDHHC16B,TRIM61,ZDHHC15,LDB3A,KPNB1,PIAS2 |
| metalloendopeptidase activity | TLL2,PITRM1,TLL1,ADAMTS2,ADAM1B,MMP25,ADAM33,MMP16,ECE2,ADAMTS12 |
Interacting Protein
PHEX has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PHEX here. Most of them are supplied by our site. Hope this information will be useful for your research of PHEX.
q81xb4_bacan
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References
- Li, F; Song, N; et al. Pigment Epithelium Derived Factor Suppresses Expression of Sost/Sclerostin by Osteocytes: Implication for Its Role in Bone Matrix Mineralization. JOURNAL OF CELLULAR PHYSIOLOGY 230:1243-1249(2015).
- Han, SW; Tamaki, T; et al. A Novel Osteoblast/Osteocyte Selection Method in Primary Isolated Chick Bone Cells by Atomic Force Microscopy. JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY 15:3923-3927(2015).
