OTUB1
-
Official Full Name
OTU domain, ubiquitin aldehyde binding 1 -
Overview
Protein ubiquitination and deubiquitination are reversible processes catalyzed by ubiquitinating enzymes (UBEs) and deubiquitinating enzymes (DUBs). DUBs are categorized into 5 subfamilies: USP, UCH, OTU, MJD, and JAMM. The OTU subfamily comprises a group -
Synonyms
OTUB1;OTU domain, ubiquitin aldehyde binding 1;ubiquitin thioesterase OTUB1;FLJ20113;FLJ40710;otubain-1;OTU-domain Ubal-binding 1;deubiquitinating enzyme OTUB1;ubiquitin-specific protease otubain 1;ubiquitin-specific-processing protease OTUB1;OT
Recombinant Proteins
- Human
- Mouse
- Rat
- E.coli
- Mammalian Cell
- HEK293
- E. coli
- HEK293T
- Mammalian cells
- His
- GST
- Non
- Flag
- GST&FLag
- His&Fc&Avi
- Myc&DDK
Involved Pathway
OTUB1 involved in several pathways and played different roles in them. We selected most pathways OTUB1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with OTUB1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
OTUB1 has several biochemical functions, for example, NEDD8-specific protease activity,protein binding,ubiquitin binding. Some of the functions are cooperated with other proteins, some of the functions could acted by OTUB1 itself. We selected most functions OTUB1 had, and list some proteins which have the same functions with OTUB1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| NEDD8-specific protease activity | OTUB1A,OTUB2,OTUB1B |
| ubiquitin-specific protease activity | IWS1,USP48,USP8,COPS5,USP9,USP1,OTUD5A,USP27X,OTUD7B,USP2 |
| protein binding | ADA,BACH1,CRY1,NUP54,ASL,DSP,SMG5,LEO1,LRPAP1,ZFYVE9 |
| ubiquitin binding | NEDD4,FAN1,FAF1,USP25,IWS1,D17WSU92E,OTUB1B,FAM125A,VPS28,RNF31 |
| ubiquitin protein ligase binding | GABARAPL1,SQSTM1,PML,DNM1L,SPOP,CKB,TUBA1B,LC3,ZFP746,HSPA5 |
Interacting Protein
OTUB1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with OTUB1 here. Most of them are supplied by our site. Hope this information will be useful for your research of OTUB1.
UBE2D3;UBE2D2;TP53
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