OCA2
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Official Full Name
oculocutaneous albinism II -
Overview
This gene encodes the human homologue of the mouse p (pink-eyed dilution) gene. The encoded protein is believed to be an integral membrane protein involved in small molecule transport, specifically tyrosine - a precursor of melanin. Mutations in this gene result in type 2 oculocutaneous albinism. -
Synonyms
OCA2;oculocutaneous albinism II;P protein;BEY;BEY1;BEY2;EYCL;melanocyte specific transporter protein;BOCA;D15S12;EYCL2;HCL3;PED;EYCL3;eye color 2 (central brown);eye color 3 (brown);hair color 3 (brown);Melanocyte-specific transporter protein;oculocutaneous albinism II (pink-eye dilution homolog, mouse);P;P_HUMAN;Pink eyed dilution protein homolog;Pink-eyed dilution protein homolog;SHEP1;total brown iris pigmentation
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| OCA2-2919H | Recombinant Human OCA2 protein, His-tagged | E.coli | Human | His | 1-174 aa | |
| OCA2-11062M | Recombinant Mouse OCA2 Protein | Mammalian Cell | Mouse | His |
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| OCA2-30532TH | Recombinant Human OCA2 | Wheat Germ | Human | Non | 100 amino acids |
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| OCA2-6306M | Recombinant Mouse OCA2 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| OCA2-6306M-B | Recombinant Mouse OCA2 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
OCA2 involved in several pathways and played different roles in them. We selected most pathways OCA2 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with OCA2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
OCA2 has several biochemical functions, for example, L-tyrosine transmembrane transporter activity,protein binding,transporter activity. Some of the functions are cooperated with other proteins, some of the functions could acted by OCA2 itself. We selected most functions OCA2 had, and list some proteins which have the same functions with OCA2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| transporter activity | FABP7,VPS9D1,SYPL1,AQP8A.2,SLC2A13B,ABCD1,SYPL2,SLC51B,ABCA6,Csn1s2b |
| protein binding | ERLIN1,PEPD,PKMYT1,ITPKB,ZEB1,SCIMP,KCNQ4,POLR2J,TMSB10,Cd79a |
Interacting Protein
OCA2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with OCA2 here. Most of them are supplied by our site. Hope this information will be useful for your research of OCA2.
ATP13A2
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