Nxph1
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Official Full Name
neurexophilin 1 -
Overview
This gene is a member of the neurexophilin family and encodes a secreted protein with a variable N-terminal domain, a highly conserved, N-glycosylated central domain, a short linker region, and a cysteine-rich C-terminal domain. This protein forms a very tight complex with alpha neurexins, a group of proteins that promote adhesion between dendrites and axons. -
Synonyms
NXPH1;neurexophilin 1;neurexophilin-1;NPH1;Nbla00697
Recombinant Proteins
- Rat
- Human
- Zebrafish
- Mouse
- HEK293
- Mammalian cells
- Mammalian Cell
- E.coli
- Human Cell
- His
- His&GST
- Non
- His&Fc&Avi
Involved Pathway
Nxph1 involved in several pathways and played different roles in them. We selected most pathways Nxph1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with Nxph1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
Nxph1 has several biochemical functions, for example, receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by Nxph1 itself. We selected most functions Nxph1 had, and list some proteins which have the same functions with Nxph1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| receptor binding | CX3CL1,NMU,POMC,ARRB2,HFE,ENSA,LTB,FGF8B,KCNA5,TMEM38A |
Interacting Protein
Nxph1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Nxph1 here. Most of them are supplied by our site. Hope this information will be useful for your research of Nxph1.
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References
- Reissner, C; Stahn, J; et al. Dystroglycan Binding to alpha-Neurexin Competes with Neurexophilin-1 and Neuroligin in the Brain. JOURNAL OF BIOLOGICAL CHEMISTRY 289:27585-27603(2014).
- Born, G; Breuer, D; et al. Modulation of synaptic function through the alpha-neurexin-specific ligand neurexophilin-1. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 111:E1274-E1283(2014).
