NT5C2
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Official Full Name
5-nucleotidase, cytosolic II -
Overview
This gene encodes a hydrolase that serves as an important role in cellular purine metabolism by acting primarily on inosine 5-monophosphate and other purine nucleotides. -
Synonyms
NT5C2;5-nucleotidase, cytosolic II;5 nucleotidase (purine), cytosolic type B , NT5B;cytosolic purine 5-nucleotidase;cN II;GMP;PNT5;purine 5 nucleotidase;IMP-specific 5-NT;cytosolic 5-nucleotidase II;5-nucleotidase (purine), cytosolic type B;NT5
Recombinant Proteins
- Human
- Chicken
- Rhesus macaque
- Mouse
- E.coli
- HEK293
- Wheat Germ
- Mammalian Cells
- In Vitro Cell Free System
- His
- GST
- Myc&DDK
- T7
- Non
- His&Fc&Avi
- Flag
Involved Pathway
NT5C2 involved in several pathways and played different roles in them. We selected most pathways NT5C2 participated on our site, such as Purine metabolism,Pyrimidine metabolism,Nicotinate and nicotinamide metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with NT5C2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Pyrimidine metabolism | CMPK,POLA2,PNP5A,TXNRD1,ENTPD4,POLR2C,RRM1,NT5E,NT5C3B,POLR2L |
| Metabolic pathways | ACSL3A,Ckmm,DDOST,COX5A,DAO1,EHHADH,MECR,MOGS,HSD17B12B,POLR2EB |
| Nicotinate and nicotinamide metabolism | NAPRT1,NMNAT2,NT5C1AA,NADSYN1,QPRT,NNT,NADK,NADKB,MIBP,NT5C |
| Purine metabolism | AK5,AK1,POLR2J3,PDE6B,PKMB,ADK,PRIM1,IMPDH1,POLD1,PDE10A |
Protein Function
NT5C2 has several biochemical functions, for example, 5-nucleotidase activity,metal ion binding,nucleoside phosphotransferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by NT5C2 itself. We selected most functions NT5C2 had, and list some proteins which have the same functions with NT5C2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| nucleotide binding | NELFE,RTCD1,SMOK2B,NT5E,PPIE,PFKMA,NT5M,VSIG8B,TRIO,NOL8 |
| metal ion binding | PVALB1,HDHD2,SCRT1B,ITGA5,RUFY2,ZBTB3,ZNF567,MTF1,NKD2B,RXRBA |
| protein binding | FAM120B,TAS2R16,ACHE,NLK,RUFY1,PI4K2A,AIMP1,ZNF217,KRT18,C12orf40 |
| 5-nucleotidase activity | NT5C1AA,NT5DC1,NT5C1A,NT5C1BA,ACPP,NT5DC3,NT5C,NT5DC2,NT5C2B,NT5C1B |
Interacting Protein
NT5C2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NT5C2 here. Most of them are supplied by our site. Hope this information will be useful for your research of NT5C2.
NME7;FXR2;NUDT18;MOB3B;SDCBP;ATP5O;MOB3C
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