NRXN3
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Official Full Name
neurexin 3 -
Synonyms
NRXN3;neurexin 3;C14orf60, chromosome 14 open reading frame 60;neurexin-3-beta;KIAA0743;neurexin III;neurexin III-beta;neurexin III-alpha;C14orf60;MGC176711
Recombinant Proteins
- Human
- Mouse
- Rat
- Chicken
- E.coli
- Human
- HEK293
- Mammalian cells
- Mammalian Cell
- Human Cell
- HEK293T
- E.coli expression system
- GST
- Non
- Fc
- His
- His&Fc&Avi
- His&GST
- Flag
- Myc&DDK
Involved Pathway
NRXN3 involved in several pathways and played different roles in them. We selected most pathways NRXN3 participated on our site, such as Cell adhesion molecules (CAMs), which may be useful for your reference. Also, other proteins which involved in the same pathway with NRXN3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Cell adhesion molecules (CAMs) | VCAM1,CLDN23,CLDNK,NRXN1A,ESAM,CDH2,CD40LG,CNTNAP2,Itgam&Itgb2,HLA-DRB5 |
Protein Function
NRXN3 has several biochemical functions, for example, calcium channel regulator activity,cell adhesion molecule binding,metal ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by NRXN3 itself. We selected most functions NRXN3 had, and list some proteins which have the same functions with NRXN3. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| transmembrane signaling receptor activity | FZD1,OR6K3,CD3G,CELSR3,FZD7B,CD79A,IL1R1,TLR7,P2RX5,PTH1RB |
| metal ion binding | MT1HL1,ZFP36L3,TM9SF1,SIAH1A,ZC3H18,TRIM46B,REST,ZNF614,U2AF1L4,MGAT5B |
| cell adhesion molecule binding | LPHN1,DSG2,NRXN2,JUP,ITGB7,NLGN3,FGG,PVRL1A,Fert2,SELL |
| calcium channel regulator activity | STIM2,NPY,PRKCB,GRM2,SGK2A,SGK1,STIM1A,NPY2R,CRISP1,NRXN1 |
| receptor activity | CD46,OPN1SW,IL10RB,CD86,NLGN4Y,SIGLEC7,TLR6,MED13,GUCY1B3,GRIA2B |
| neuroligin family protein binding | NRXN2,DLG4,NRXN1 |
Interacting Protein
NRXN3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NRXN3 here. Most of them are supplied by our site. Hope this information will be useful for your research of NRXN3.
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References
- Budreck, EC; Scheiffele, P; et al. Neuroligin-3 is a neuronal adhesion protein at GABAergic and glutamatergic synapses. EUROPEAN JOURNAL OF NEUROSCIENCE 26:1738-1748(2007).
- Chubykin, AA; Liu, XR; et al. Dissection of synapse induction by neuroligins - Effect of a neuroligin mutation associated with autism. JOURNAL OF BIOLOGICAL CHEMISTRY 280:22365-22374(2005).
