NLGN4X
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Official Full Name
neuroligin 4, X-linked -
Synonyms
NLGN4X;neuroligin 4, X-linked;neuroligin 4, NLGN4;neuroligin-4, X-linked;HLNX;KIAA1260;NLGN;neuroligin X;HNLX;HNL4X;NLGN4;ASPGX2;AUTSX2;MGC22376
Recombinant Proteins
- Human
- Chicken
- HEK293
- Mammalian Cells
- E.coli
- Wheat Germ
- His
- Fc
- Non
- His&Fc&Avi
- Myc&DDK
- GST
Involved Pathway
NLGN4X involved in several pathways and played different roles in them. We selected most pathways NLGN4X participated on our site, such as Cell adhesion molecules (CAMs), which may be useful for your reference. Also, other proteins which involved in the same pathway with NLGN4X were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Cell adhesion molecules (CAMs) | Icosl,CLDN15LB,ITGB2,ALCAMA,PVR,CLDN22,CLDNE,CLDNC,ITGA6,CD40 |
Protein Function
NLGN4X has several biochemical functions, for example, cell adhesion molecule binding,chloride ion binding,NOT cholinesterase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by NLGN4X itself. We selected most functions NLGN4X had, and list some proteins which have the same functions with NLGN4X. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| receptor activity | PROCR,NR2C2,MED17,Pla2r1,CXCR3,CADM1,SMAGP,CD93,TACSTD2,PVRL4 |
| protein binding | BAIAP2,MTERFD2,GNB3,DNAJC11,COX4I1,STX6,FNBP1,FGF21,CCNE2,ECE1 |
| neurexin family protein binding | NLGN3A,CASK,NLGN4Y,NLGN1,NLGN2,SYTL2,NLGN3B,SYTL3,NLGN4B,NLGN2A |
| protein homodimerization activity | TSG101,AMBP,ASMT,Trl,CADM4,SFTPC,XPNPEP1,NLRC4,SNF8,LSM1 |
| chloride ion binding | SLC22A6,ACE,CTSC,AMY2A,Amy1 |
| scaffold protein binding | CACNA1G,KRT18,VIM,NOS3,CHRNA7,MDM2,MAPK3,LRP4,KCNQ1,GRID2 |
| cell adhesion molecule binding | CAML,CADM1,ITGB1,NLGN3,POSTN,EZR,PVRL4,PTBP3,SELL,PVRL2 |
| NOT cholinesterase activity | NLGN2,NLGN4Y,NLGN2A,NLGN4B,NLGN4A,NLGN3,NLGN2B,NLGN3A,NLGN1,NLGN3B |
Interacting Protein
NLGN4X has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NLGN4X here. Most of them are supplied by our site. Hope this information will be useful for your research of NLGN4X.
Nrxn1;astD;BRK1
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References
- Daoud, H; Bonnet-Brilhault, F; et al. Autism and Nonsyndromic Mental Retardation Associated with a De Novo Mutation in the NLGN4X Gene Promoter Causing an Increased Expression Level. BIOLOGICAL PSYCHIATRY 66:906-910(2009).
- Pampanos, A; Volaki, K; et al. A Substitution Involving the NLGN4 Gene Associated with Autistic Behavior in the Greek Population. GENETIC TESTING AND MOLECULAR BIOMARKERS 13:611-615(2009).
