NFIL3
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Official Full Name
nuclear factor, interleukin 3, regulated -
Overview
Expression of interleukin-3 (IL3; MIM 147740) is restricted to activated T cells, natural killer (NK) cells, and mast;cell lines. Transcription initiation depends on the activating capacity of specific protein factors, such as NFIL3,;that bind to regulatory regions of the gene, usually upstream of the transcription start site (Zhang et al., 1995;(PubMed 7565758)). -
Synonyms
NFIL3;nuclear factor, interleukin 3, regulated;nuclear factor interleukin-3-regulated protein;E4 promoter binding-protein 4;E4 promoter-binding protein 4;embryo implantation-related NFIL3/E4BP4-like transcription factor;E4BP4;AV225605
Recombinant Proteins
- Human
- Mouse
- Zebrafish
- Rhesus macaque
- Rat
- Chicken
- E.coli
- Mammalian Cell
- HEK293
- HIS
- His
- His&T7
- Non
- His&Fc&Avi
Involved Pathway
NFIL3 involved in several pathways and played different roles in them. We selected most pathways NFIL3 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with NFIL3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
NFIL3 has several biochemical functions, for example, DNA binding,RNA polymerase II core promoter sequence-specific DNA binding,RNA polymerase II regulatory region sequence-specific DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by NFIL3 itself. We selected most functions NFIL3 had, and list some proteins which have the same functions with NFIL3. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| DNA binding | ELK4,HOXB4A,POLE3,ZFP653,ZNF580,PBX1,NFYC,AHR2,INSM1A,ZNF367 |
| RNA polymerase II core promoter sequence-specific DNA binding | SMYD3,SOX8,ZNF277,SMAD5,TBR1,SFPI1,ZFP335,ZNF335,RBPJ,WBP2 |
| transcription corepressor activity | EID1,ATF7IP,NANOG,TBL1Y,KCTD1,PBXIP1,UBP1,RUNX1T1,YAF2,NCOR1 |
| RNA polymerase II regulatory region sequence-specific DNA binding | SP5,CREBBP,NHLH2,ATF3,ZSCAN20,SOX13,FOXC1,ZFAT,CDX1B,TRPS1 |
| transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding | HMGA2,NFE2L3,NFIL3-6,HHEX,NKX6-1,GFI1,HSF1,TCF3,TBX15,ZGPAT |
| transcription factor activity, sequence-specific DNA binding | HOXA13,TRP53,MTF1,VDRB,ZNF691,THRAA,ZKSCAN17,KLF17,EOMESB,DMRTA2 |
| protein binding | TMEM27,DCTN2,PPP2R5E,TDRD7,RPF1,FKBP1B,PIK3R3,ZFYVE19,PYDC1,CHMP4A |
Interacting Protein
NFIL3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NFIL3 here. Most of them are supplied by our site. Hope this information will be useful for your research of NFIL3.
TRAF2;meq_gahvm;AMOTL2;il3_human_-160/-141_dna-probe
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