NARS
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Official Full Name
asparaginyl-tRNA synthetase -
Overview
Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids.Asparaginyl-tRNA synthetase is localized to the cytoplasm and belongs to the class II family of tRNA synthetases.The N-terminal domain represents the signature sequence for the eukaryotic asparaginyl-tRNA synthetases. -
Synonyms
NARS;asparaginyl-tRNA synthetase;asparaginyl-tRNA synthetase, cytoplasmic;asparagine tRNA ligase 1;cytoplasmic;NARS1;3010001M15Rik;AA960128;ASNRS;ASNS;Asparagine tRNA ligase 1, cytoplasmic;Asparagine tRNA ligase;Asparagine--tRNA ligase;Asparaginyl tRNA synthetase;C78150;EC 6.1.1.22;LRRGT00113;MGC116236;NRS;SYNC_HUMAN
Recombinant Proteins
- Mouse
- Human
- Chicken
- Mycobacterium Tuberculosis
- Mammalian Cell
- Wheat Germ
- E.coli
- HEK293T
- HEK293
- Insect Cell
- E.coli expression system
- His
- Non
- His&T7
- His&GST
- Myc&DDK
- His&Fc&Avi
Involved Pathway
NARS involved in several pathways and played different roles in them. We selected most pathways NARS participated on our site, such as Aminoacyl-tRNA biosynthesis, which may be useful for your reference. Also, other proteins which involved in the same pathway with NARS were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Aminoacyl-tRNA biosynthesis | FARSA,HARS2,TARS,VARS2,MADD,TARSL2,GATC,FARSB,CARS,WARS |
Protein Function
NARS has several biochemical functions, for example, ATP binding,asparagine-tRNA ligase activity,nucleic acid binding. Some of the functions are cooperated with other proteins, some of the functions could acted by NARS itself. We selected most functions NARS had, and list some proteins which have the same functions with NARS. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| asparagine-tRNA ligase activity | NARS2 |
| nucleic acid binding | ZFP622,RBM4.1,ZFP14,KLF12A,INSM1B,UMPS,BICC2,REXO2,SFRS3A,EAR1 |
| ATP binding | AFG3L2,AK5,TGFBR1B,JAK1,UPF1,TCP1,ATP2B2,MUSK,ACSS1,DNAJA3A |
Interacting Protein
NARS has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NARS here. Most of them are supplied by our site. Hope this information will be useful for your research of NARS.
IKBKE;LSM1;ATXN1;deoB;ssrna_ug;FN1;IFI16;HDAC2
Resources
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References
- Kovalenko, OV; Olland, A; et al. Atypical Antigen Recognition Mode of a Shark Immunoglobulin New Antigen Receptor (IgNAR) Variable Domain Characterized by Humanization and Structural Analysis. JOURNAL OF BIOLOGICAL CHEMISTRY 288:17408-17419(2013).
- Liu, NJ; Schnell, S; et al. Sex, Pain, and Opioids: Interdependent Influences of Sex and Pain Modality on Dynorphin-Mediated Antinociception in Rats. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 344:522-530(2013).
