NAPSA
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Official Full Name
napsin A aspartic peptidase -
Overview
The activation peptides of aspartic proteinases plays role as inhibitors of the active site. These peptide segments, or pro-parts, are deemed important for correct folding, targeting, and control of the activation of aspartic proteinase zymogens. The pronapsin A gene is expressed predominantly in lung and kidney. Its translation product is predicted to be a fully functional, glycosylated aspartic proteinase precursor containing an RGD motif and an additional 18 residues at its C-terminus. -
Synonyms
NAPSA;napsin A aspartic peptidase;KAP;Kdap;NAP1;NAPA;SNAPA;napsin-A;ASP4;asp 4;napsin-1;TA01/TA02;pronapsin A;aspartyl protease 4;kidney-derived aspartic protease-like protein;EC 3.4.23;EC 3.4.23.15;EC 3.4.23.3;EC 3.4.23.5
Recombinant Proteins
- Human
- Mouse
- E.coli
- Mammalian Cell
- HEK293
- His
- Non
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| NAPSA-1182H | Recombinant Human NAPSA, His-tagged | E.coli | Human | His | 1-420aa | |
| NAPSA-10427M | Recombinant Mouse NAPSA Protein | Mammalian Cell | Mouse | His |
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| NAPSA-3969HCL | Recombinant Human NAPSA 293 Cell Lysate | HEK293 | Human | Non |
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| NAPSA-3262H | Recombinant Human NAPSA protein, His-tagged | E.coli | Human | His | 64-420aa |
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| Napsa-4643M | Recombinant Mouse Napsa protein, His-tagged | E.coli | Mouse | His | 73-394aa |
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| NAPSA-5909M | Recombinant Mouse NAPSA Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| NAPSA-5909M-B | Recombinant Mouse NAPSA Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
NAPSA involved in several pathways and played different roles in them. We selected most pathways NAPSA participated on our site, such as Lysosome, which may be useful for your reference. Also, other proteins which involved in the same pathway with NAPSA were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Lysosome | DNASE2A,GM2A,AP3B1,GAA,AP1G2,AGA,ATP6AP1,PPT2,ACP5A,SUMF1 |
Protein Function
NAPSA has several biochemical functions, for example, aspartic-type endopeptidase activity,endopeptidase activity,peptidase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by NAPSA itself. We selected most functions NAPSA had, and list some proteins which have the same functions with NAPSA. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| aspartic-type endopeptidase activity | ASPRV1,ATP6AP2,DDI1,Ren1,PSEN2,PGA4,CNTNAP5A,BACE2,PGA5,PGA |
| peptidase activity | CAPN3,METAP2,CAPN11,ASTL,METAP2A,TMPRSS13A,GZMC,PARK7,CTSBA,ZMPSTE24 |
| endopeptidase activity | ADAM10,KLK1B3,CASP1,MMP12,PSEN1,TRAPPC12,KLK1B24,SENP5,PSEN2,CD46 |
Interacting Protein
NAPSA has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NAPSA here. Most of them are supplied by our site. Hope this information will be useful for your research of NAPSA.
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