MUC2
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Official Full Name
mucin 2, oligomeric mucus/gel-forming -
Overview
Mucins are high molecular weight glycoproteins which constitute the major component of the mucus layer that protects the gastric epithelium from chemical and mechanical aggressions. In humans, at least 14 mucin genes have been identified that code for the -
Synonyms
MUC2;mucin 2, oligomeric mucus/gel-forming;mucin 2, intestinal/tracheal;mucin-2;intestinal mucin-2;mucin-like protein;MLP;SMUC;MUC-2
Recombinant Proteins
- Human
- Pig
- Mouse
- Rat
- E.coli
- Pig
- Mouse
- Yeast
- GST
- His
- Non
- His&SUMO
Involved Pathway
MUC2 involved in several pathways and played different roles in them. We selected most pathways MUC2 participated on our site, such as Vibrio cholerae infection,Amoebiasis, which may be useful for your reference. Also, other proteins which involved in the same pathway with MUC2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Vibrio cholerae infection | ATP6V1A,PRKACA,ATP6V0C,ERO1L,ATP6V1D,ATP6V0A1,ATP6V0D1,ATP6V0A2,GNAS,KDELR1 |
| Amoebiasis | COL4A5,IL12B,HSPB1,CTSG,LAMB4,PLCB3,Itgam&Itgb2,PIK3CB,PIK3R2,IL6 |
Protein Function
MUC2 has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by MUC2 itself. We selected most functions MUC2 had, and list some proteins which have the same functions with MUC2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | LUZP4,GUCY1B3,RABIF,MT2A,NUAK2,SMAD3,MIF4GD,PRKAB2,SCYL2,TPM3 |
Interacting Protein
MUC2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MUC2 here. Most of them are supplied by our site. Hope this information will be useful for your research of MUC2.
MLH1;CFTR
Resources
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References
- Cserni, G; et al. Reversed polarity of the glandular epithelial cells in micropapillary carcinoma of the large intestine and the EMA/MUC1 immunostain. PATHOLOGY 46:527-532(2014).
- Vo, DTN; Nakayama, T; et al. Progression risk assessments of individual non-invasive gastric neoplasms by genomic copy-number profile and mucin phenotype. BMC MEDICAL GENOMICS 8:-(2015).
