LSM6
-
Official Full Name
LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae) -
Overview
Sm-like proteins were identified in a variety of organisms based on sequence homology with the Sm protein family (see SNRPD2; MIM 601061). Sm-like proteins contain the Sm sequence motif, which consists of 2 regions separated by a linker of variable length that folds as a loop. The Sm-like proteins are thought to form a stable heteromer present in tri-snRNP particles, which are important for pre-mRNA splicing. -
Synonyms
LSM6;LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae);U6 snRNA-associated Sm-like protein LSm6;YDR378C;LSM 6;LSM6 homolog U6 small nuclear RNA associated;Sm protein F;U6 snRNA associated Sm like protein LSm6;OTTHUMP00000220223;OTTHUMP00000220224;OTTHUMP00000220225;OTTHUMP00000221100
Recombinant Proteins
- Rhesus macaque
- Zebrafish
- Chicken
- Mouse
- Human
- Mammalian Cell
- HEK293
- HEK293T
- Wheat Germ
- In Vitro Cell Free System
- His
- Non
- His&Fc&Avi
- Myc&DDK
- GST
Involved Pathway
LSM6 involved in several pathways and played different roles in them. We selected most pathways LSM6 participated on our site, such as Deadenylation-dependent mRNA decay,Gene Expression,RNA degradation, which may be useful for your reference. Also, other proteins which involved in the same pathway with LSM6 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Deadenylation-dependent mRNA decay | TNKS1BP1,EXOSC8,EIF4E,C2orf29,D1BWG0212E,EIF4G1,EIF4B,EIF4A2,EIF4A1,PAIP1 |
| Spliceosome | SRSF5B,SRSF1A,TCERG1,SF3B4,SRSF5,PRPF19,SNW1,SRSF2B,SMX5,CHERP |
| Gene Expression | POLR3C,ZNF557,ZNF486,DHX9,ZNF566,ZNF223,SKIA,CCNT2B,ZNF37A,GTF3AB |
| mRNA decay by 5 to 3 exoribonuclease | DDX6,DCP1B |
| RNA degradation | TOB2,CNOT10,HSPD1,PARN,LSM8,DHX36,DIS3,BTG3,BTG2,ENO1B |
Protein Function
LSM6 has several biochemical functions, for example, poly(A) RNA binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by LSM6 itself. We selected most functions LSM6 had, and list some proteins which have the same functions with LSM6. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| poly(A) RNA binding | DHX15,EWSR1,MRPL13,HIST1H4D,C14orf21,RPS21,YTHDC2,MRPS7,NGDN,MANF |
| protein binding | CLTC,AP1G1,KIF4A,NFIL3,TAX1BP1,Itga10&Itgb1,RNF43,GAS6,UTP3,GDAP2 |
Interacting Protein
LSM6 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with LSM6 here. Most of them are supplied by our site. Hope this information will be useful for your research of LSM6.
LSM5;CLNS1A;LSM3;SDCBP
Resources
Related Services
Related Products
References
- Perea-Resa, C; Hernandez-Verdeja, T; et al. LSM Proteins Provide Accurate Splicing and Decay of Selected Transcripts to Ensure Normal Arabidopsis Development. PLANT CELL 24:4930-4947(2012).
- Novotny, I; Podolska, K; et al. Nuclear LSm8 affects number of cytoplasmic processing bodies via controlling cellular distribution of Like-Sm proteins. MOLECULAR BIOLOGY OF THE CELL 23:3776-3785(2012).
