LIPG
-
Official Full Name
lipase, endothelial -
Overview
The protein encoded by this gene has substantial phospholipase activity and may be involved in lipoprotein metabolism and vascular biology. This protein is designated a member of the TG lipase family by its sequence and characteristic lid region which provides substrate specificity for enzymes of the TG lipase family. [provided by RefSeq, Jul 2008] -
Synonyms
LIPG;lipase, endothelial;EL;EDL;PRO719;endothelial lipase;lipoprotein lipase H;endothelial cell-derived lipase
Recombinant Proteins
- Human
- Zebrafish
- Rat
- Mouse
- HEK293
- Mammalian Cell
- E.coli
- HEK293T
- Mammalian cells
- His
- Non
- His&Fc&Avi
- Myc&DDK
- Flag
Involved Pathway
LIPG involved in several pathways and played different roles in them. We selected most pathways LIPG participated on our site, such as Glycerolipid metabolism,Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with LIPG were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Glycerolipid metabolism | MBOAT2B,ALDH1B1,GPAM,AGPAT6,AGPAT9,PPAP2CB,LIPF,MBOAT1,DGKB,LIPCA |
| Metabolic pathways | DTYMK,CYP2P9,B3GALT5,GALNT10,IDO1,CYP7A1A,GUK1B,ADSSL1,GAD2,COX5B |
Protein Function
LIPG has several biochemical functions, for example, heparin binding,lipoprotein lipase activity,phosphatidylcholine 1-acylhydrolase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by LIPG itself. We selected most functions LIPG had, and list some proteins which have the same functions with LIPG. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| lipoprotein lipase activity | LPL,AOAH |
| heparin binding | HDGF,LTBP2,LPL,FGF2,FGF1A,COL5A1,EPYC,WISP3,APOA5,CYR61L1 |
| phosphatidylcholine 1-acylhydrolase activity | ABHD3,PLA1A,PLA2G16 |
| phospholipase activity | PLA2G10,PLA2G4AA,LIPI,ABHD2B,PNLIPRP2,LIPC,CES1C,LIPH,LIPM,CELL |
Interacting Protein
LIPG has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with LIPG here. Most of them are supplied by our site. Hope this information will be useful for your research of LIPG.
kinD;EXOSC5
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References
- Cole, CB; Nikpay, M; et al. Adiposity significantly modifies genetic risk for dyslipidemia. JOURNAL OF LIPID RESEARCH 55:2416-2422(2014).
- Browne, RW; Weinstock-Guttman, B; et al. Serum lipoprotein composition and vitamin D metabolite levels in clinically isolated syndromes: Results from a multi-center study. JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY 143:424-433(2014).
